调理通宝Ⅰ号胶囊的质量标准  

Quality Standard for Tiaolitongbao Ⅰ Capsules

作　　者：李晰[1] 刘梅[1] 吴丹[1] 张旸[1] 张琰[1] 

机构地区：[1]第四军医大学唐都医院药剂科,西安710038

出　　处：《中国药师》2017年第8期1474-1476,共3页China Pharmacist

基　　金：军队医疗机构制剂标准提高专项课题(编号:13ZJZ12-6)

摘　　要：目的:建立调理通宝Ⅰ号胶囊的质量标准。方法:采用薄层色谱法鉴别黄芪、白术、佛手、木香,采用高效液相色谱法测定虎杖中有效成分大黄素的含量。结果:TLC鉴别斑点清晰,阴性对照无干扰。虎杖中有效成分大黄素在线性范围4.25~68.00μg·ml^(-1)内线性关系良好,r=0.999 9;平均加样回收率为95.22%,RSD为1.47%(n=6)。结论:通过方法学验证表明所建立的方法可用于调理通宝Ⅰ号胶囊的质量控制。Objective： To establish the quality standard for Tiaolitongbao I capsules. Methods： The components including Astrag- alus, Atractylodes, Finger citron and Radix aucklandiae were identified by TLC. Emodin, the effective component of Polygonum cuspi- datum, was determined by HPLC. Results： The characteristic spots in TLC were clear without any interference. The linear range of emodin was 4.25-68.00 μg·ml-1 （ r = 0. 999 9 ）. The average recovery was 95.22% , and RSD was 1.47% （ n = 6 ）. Conclusion ： The methods used for the identification and quantification are sensitive, simple and accurate, which can be used for the quality control of Tiaolitongbao I capsules.

关 键 词：调理通宝Ⅰ号胶囊 质量标准 薄层色谱法 高效液相色谱法 

分 类 号：TQ460.72[医药卫生—药物分析学]