Gd^(3+)doped CuInS_(2)/ZnS nanocrystals with high quantum yield for bimodal fluorescence/magnetic resonance imaging  

作　　者：郁彩艳 宣曈曈 楼孙棋? 刘潇潇 廉国海 李会利 

机构地区：[1]Engineering Research Centerjbr Nanophotonics&Advanced Instrument,Ministry qf Education,School of Physics and Materials Science,East China Norreal University,Shanghai 200062,China [2]Ministry of Education Key Laboratory of Bioinorganic and Synthetic Chemistry,State Key Laboratory of Optoelec-tronic Materials and Technologies,KL GHE1 of Environment and Energy Uhemistry,School of Chemistry,Sun Yat-Sen University,Guangzhou 510275,China [3]Engineering Department,Hunan Electric Power Research Institute of State Grid,Chang,sha 410007,China [4]Marketing Department,Hunan Electric Power Company of State Grid,Changsha 410007,China

出　　处：《Journal of Rare Earths》2017年第4期382-388,共7页稀土学报（英文版）

基　　金：Project supported by the National Natural Science Foundation of China(51472087);Shanghai Municipal Natural Science Foundation(13ZR1412500);Innovation Program of Shanghai Municipal Education Commission(14ZZ050);the ECNU Reward for Out-standing Doctoral Dissertation Cultivation Plan of Action(PY2015041)

摘　　要：Recently, CulnS2/ZnS nanocrystals （CISZ NCs） have been widely used in many fields due to their excellent properties, such as tunable photoluminescence （PL） spectra, broad absorption, and non-toxicity. In order to expand the application ofCISZ NCs, Gd3＋ was introduced into the host serving as paramagnetic modules to achieve magnetic resonance imaging （MRI） enhancement. MRI probes could provide high-resolution anatomical information. The derived Gd-Cu-In-S/ZnS nanocrystals （GCISZNCs） exhibited the strong orange photoluminescence with a quantum yield of 57.6% and significantly high longitudinal relaxivity （rl-20.4 mmol/s） in comparison with commmercial Magnevist （Gd-DTPA, r1=4.5mmol/s）. Effective enhancement of MRI and improved longitudinal relaxivity as well as lower cytotoxicity mode GCISZ NCs an ideal MRI probe, suggesting its potential and significance in practical biological and clinic applications in the future.Recently, CulnS2/ZnS nanocrystals （CISZ NCs） have been widely used in many fields due to their excellent properties, such as tunable photoluminescence （PL） spectra, broad absorption, and non-toxicity. In order to expand the application ofCISZ NCs, Gd3＋ was introduced into the host serving as paramagnetic modules to achieve magnetic resonance imaging （MRI） enhancement. MRI probes could provide high-resolution anatomical information. The derived Gd-Cu-In-S/ZnS nanocrystals （GCISZNCs） exhibited the strong orange photoluminescence with a quantum yield of 57.6% and significantly high longitudinal relaxivity （rl-20.4 mmol/s） in comparison with commmercial Magnevist （Gd-DTPA, r1=4.5mmol/s）. Effective enhancement of MRI and improved longitudinal relaxivity as well as lower cytotoxicity mode GCISZ NCs an ideal MRI probe, suggesting its potential and significance in practical biological and clinic applications in the future.

关 键 词：Gd-Cu-In-S/ZnS nanocrystals longitudinal relaxivity magnetic resonance imaging rare earths 

分 类 号：TB383.1[一般工业技术—材料科学与工程] R445.2[医药卫生—影像医学与核医学]