北京市丰台区二价脊髓灰质炎减毒活疫苗损耗系数分析  

Analysis on loss coefficient of bivalent live attenuated oral poliomyelitis vaccine in Fengtai district of Beijing

作　　者：王中战[1] 姜晓飞[1] 李靖琳[1] 

机构地区：[1]北京市丰台区疾病预防控制中心,北京100071

出　　处：《疾病监测》2017年第7期553-556,共4页Disease Surveillance

摘　　要：目的通过分析北京市丰台区二价脊髓灰质炎减毒活疫苗(bOPV)损耗系数,了解其损耗程度,为科学制定疫苗使用计划,规范疫苗管理提供依据。方法根据统一设计的《丰台区二价脊灰疫苗接种情况日报表》,收集丰台区所有接种单位2016年5月9-27日bOPV接种情况和使用情况。结果丰台区共67家儿童预防接种门诊开展b OPV接种。5月9-27日,b OPV损耗系数为2.10。村属社区站/部队属门诊(2.27)、行业门诊(2.22)和卫生和计划生育委员会直属门诊(1.98)损耗系数之间的差异有统计学意义。达标门诊(2.24)与规范化门诊(2.04)损耗系数之间差异有统计学意义。日均接种量<10人次损耗系数(2.39)高于10~20人次(2.12)和>20人次损耗系数(1.75),差异有统计学意义。损耗系数在每人一个滴管与无污染的情况下不更换滴管之间差异有统计学意义。损耗系数在冷藏保存30 min废弃和当日持续使用之间差异有统计学意义。结论丰台区bOPV损耗率高。为降低损耗,各接种单位应规范使用滴管和剩余疫苗,安排集中接种,减少疫苗开启数量。Objective To analyze the loss coefficient of bivalent live attenuated oral poliomyelitis vaccine （bOPV） and understand the loss extent of bOPV in Fengtai district of Beijing for the development of evidence based vaccine use plan and standardization of vaccine management. Methods A standardized daily reporting sheet of bOPV vaccination was used to collect the information about bOPV use in all vaccination clinics in Fengtai in May 2016. Results There were 67 vaccination clinics in Fengtai. From 9m to 27m in May 2016, the overall loss coefficient of bOPV was 2. 10, the loss coefficient was 2. 27 in village/military vaccination clinics, 2. 22 in enterprise vaccination clinics and 1.98 in clinics of health department, the differences were significant. The difference in loss coefficient between vaccination clinics at lower level （2. 24 ） and vaccination clinics at higher level （ 2. 04） had significant difference. The loss coefficient was higher in clinics with 〈 10 vaccination services daily （2. 39） than in clinics with 10 -20 vaccination services daily （2. 12） and with 〉 20 vaccination services （ 1.75 ）, the difference was significant. Sharing dropper or not resulted in different loss coefficient, the difference was significant. Disusing vaccine after 30 minute cold storage and continuing to use vaccine also resulted in different loss coefficient, the difference was significant. Conclusion The loss coefficient of was high in Fengtai. In order to reduce the waste of vaccine, it is necessary to use dropper and remaining vaccine according to related regulations, conduct mass vaccination and reduce the unnecessary opening the package of bOPV.

关 键 词：二价脊髓灰质炎减毒活疫苗 损耗系数 调查分析 

分 类 号：R186[医药卫生—流行病学]