新疆阿魏化学成分及药理活性研究进展  

Chemical constituents and pharmacological activities of Ferula sinkiangensis K.M.Shen:research advances

作　　者：黄雅婷[1] 岳丽君[1,2] 申翔宇[1] 王坤[1] 刘春兰[1,2] HUANG Ya-ting YUE Li-jun SHENG Xiang-yu WANG Kun LIU Chun-lan(College of Life and Environmental Science Beijing Engineering Research Center of Food Environment and Public Health, Minzu University of China, Beijing 100081, China)

机构地区：[1]中央民族大学生命与环境科学学院,北京100081 [2]中央民族大学北京市食品环境与健康工程技术研究中心,北京100081

出　　处：《国际药学研究杂志》2017年第6期495-499,共5页Journal of International Pharmaceutical Research

基　　金：中央民族大学一流大学一流学科建设项目(YLDX01013);"111创新引智计划"工程项目(B08044);准格尔北部生态保育技术集成与示范项目(2014BAC15B04)

摘　　要：新疆阿魏(Ferula sinkiangensis K.M.Shen)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分。目前多采用色谱技术建立指纹图谱实现质量控制。原植物药和特征化合物都具有抑菌、杀虫、抗过敏、抗肿瘤等广泛药理作用。本文主要从资源现状、化学成分、指纹图谱和药理活性等方面对国内外新疆阿魏的研究状况进行综述,为其系统化研究、有效质量控制和高效开发利用提供参考。Ferula sinkiangensis K.M. Shen is a kind of endangered national plant medicine in the northern of Xinjiang,China.It mainly contains sesquiterpene coumarins,sulfides,polysaccharides,aromatic compounds and other effective chemical constitutions;Chromatography is used to build the fingerprint and to control the medicine quality in most cases. Both raw plant medicine and specific compounds possess pharmacologic activities such as antibacterial,insecticidal,anti-allergic,and antitumor properties. The present paper summarizes the resource distribution,chemical constituents,fingerprints and pharmacological activities of F. sinkiangensis,to provide reference for its systematic research,effective quality control and efficient development and utilization.

关 键 词：新疆阿魏 资源分布 化学成分 指纹图谱 药理活性 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]