CuSO_4·5H_2O/NaAsc催化下碘代芳烃和末端炔烃的Sonogashira偶联反应  

CuSO_4·5H_2O/NaAsc-Catalyzed Sonogashira Coupling Reaction of Aryl Iodides and Terminal Alkynes

作　　者：戚海棠 宋光琳 权正军[1] 王喜存[1] Qi Haitang Song Guanglin Quan Zhengjun Wang Xicun(College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 73007)

机构地区：[1]西北师范大学化学化工学院,兰州730070

出　　处：《有机化学》2017年第7期1855-1859,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21362032;21362031)资助项目~~

摘　　要：采用CuSO_4·5H_2O/NaAsc的均相催化体系,实现了碘代芳烃和末端炔烃的Sonogashira反应.此催化体系替代了一般的Pd/Cu结合磷配体的催化体系,具有催化剂廉价易得,后处理简单,反应在均相条件下进行等优点,符合绿色化学的要求.In this paper, the homogeneous catalytic system of CuSO4·5H2O/NaAsc was used to realize the Sonogashira reaction of aryl iodides and terminal alkynes. This catalytic system replaces the general catalytic system of Pd/Cu-bound phosphorus ligand, which has the advantages of cheap catalyst, simple post-treatment, reaction under homogeneous conditions, and meets the requirements of green chemistry.

关 键 词：碘代芳烃 末端炔烃 CuSO4·5H2O/NaAsc Sonogashira偶联 

分 类 号：O621.251[理学—有机化学]