珠海地区沙眼衣原体感染的检测  

Detection of Chlamydia trachomatis infection in Zhuhai area

作　　者：张振林[1,2] 赵喜元[1,2] 黄琳[1,2] 徐芳[1,2] 林耀堂[1,2] 詹永聪 唐发清[1,2] ZHANG Zhen-lin ZHAO Xi-yuan HUANG Lin XU Fang LIN Yao-tang ZHAN Yong-cong TANG Fa-qing(Department of Clinical Laboratory, Zhuhai People＇s Hospital, Zhuhai , Guangdong 519000 Department of Clinical Laboratory, Zhuhai Hospital Affiliated to Jinan University, Zhuhai, Guangdong 519000, China)

机构地区：[1]珠海市人民医院检验科,广东珠海519000 [2]暨南大学附属珠海医院检验科,广东珠海519000

出　　处：《热带医学杂志》2017年第7期966-969,共4页Journal of Tropical Medicine

摘　　要：目的了解珠海地区沙眼衣原体感染的检测情况及流行病学特征,为沙眼衣原体感染的诊治和防控提供科学依据。方法采用免疫层析法检测沙眼衣原体抗原,采用实时荧光PCR法检测沙眼衣原体核酸,然后对资料和检测结果进行统计学分析。结果 2014年1月至2016年12月共检测标本16 232例,阳性标本753例,总阳性率为4.64%(753/16 232),阳性率呈逐年上升趋势(χ2=25.838,P=0.000),分别为:3.73%(2014)、4.62%(2015)和5.82%(2016);男女性别比为1.22∶1,男女性的阳性率分别为:4.69%(414/8 819)和4.57%(339/7 413);阳性高峰年龄主要集中在20~、30~、40~岁,构成比分别占53.12%、31.08%和10.09%,阳性率分别为:5.65%、3.96%和3.21%;男女性之间的阳性率比较在20~、30~和40~岁差异均有统计学意义(P<0.05),分别为:5.07%和6.31%、4.68%和3.12%、3.86%和2.34%。阳性结果的诊区分布显示,妇科、男科和泌尿外科占据了大部分比例,构成比分别占:42.10%、39.44%和8.63%,阳性率分别为:4.08%、4.72%和9.45%。阳性结果中有症状和无症状的比例为1.05∶1,差异有统计学意义(χ2=9.577,P=0.008)。结论珠海地区沙眼衣原体感染的流行状况依然严峻,应采取相关的预防措施和健康宣教策略以期控制泌尿生殖道沙眼衣原体的流行感染。Objective To investigate and analyze the detection and epidemiological characteristics of Chlamydia trachomatis infection in Zhuhai area ,and provide scientific basis for the diagnosis ,treatment and prevention of Chlamydia trachomatis infection. Methods The samples of Chlamydia trachomatis antigen and nucleic acid were detected by immunochromatographic assay and real-time fluorescence PCR ,respectively. The data and test results were statistically analyzed used by SPSS 19.0. Results From January 2014 to December 2016 a total of 16232 cases were detected ,with 753 positive samples,the total positive rate was 4.64%（753/16232）,and the positive rate increased year by year[χ^2 =25.838,P=0.000,3.73%（2014）,4.62%（2015）and 5.82%（2016）]. Male and female gender ratio was 1.22：1,and the positive rates of men and women were 4.69%（414/8819）and 4.57%（339/7413）,respectively. The positive peak age mainly concentrated in 20～,30～,40～ years old,accounted for 53.12%,31.08% and 10.09%,respectively,and the positive rateswere respectively 5.65%,3.96%and 3.21%. The differences in positive rates between men and women in 20～, 30～,40～ years old were statistically significant （P〈0.05）[5.07%,6.31%,and 4.68%,respectively for male;3.12%, 3.86% and 2.34%,respectively for female]. The positive cases were mainly distributed among the Andrology ,Gynecology and Urology Departments ,accounted for 42.10% ,39.44% and 8.63%,respectively ,with the positive rates of 4.08%, 4.72%and 9.45%,respectively. The ratio of positive cases with symptoms to without symptoms was 1.05：1（χ^2=9.577,P=0.008）. Conclusion The epidemic situation of Chlamydia trachomatis infection was still grim in Zhuhai. Relevant preventive measures and health education strategies should be implemented to control the genitourinary tract Chlamydia trachomatis infection.

关 键 词：沙眼衣原体 泌尿生殖道 性传播疾病 

分 类 号：R518.3[医药卫生—内科学]