沈阳市15～30岁学生HIV／AIDS患者抗病毒治疗相关因素分析  

Factors related to antiretroviral therapy among HIV/AIDS positive students aged 15-30, in a hospital of Shenyang city

作　　者：胡清海[1,2] 丁海波[1,2] 虞炎秋[1,2] 楚振兴[1,2] 徐俊杰[1,2] 尚红[1,2] Hu Qinghai Ding Haibo Yu Yanqiu Chu Zhenxing Xu Junjie Shang Hong(Key Laboratory of AIDS Immunology of National Health and Family Planning Commission, The First Affiliated Hospital of China Medical University, Shenyang 110001, China Collaborative Innovation Center for Diagnosis and Treatment of lnfectious Diseases, Hangzhou 310000, Chin)

机构地区：[1]中国医科大学附属第一医院国家卫生和计划生育委员会艾滋病免疫学重点实验室,沈阳110001 [2]感染性疾病诊治协同创新中心,杭州310000

出　　处：《中华流行病学杂志》2017年第8期1078-1082,共5页Chinese Journal of Epidemiology

摘　　要：目的 探讨沈阳市学生HIV/AIDS患者抗病毒治疗（ART）的影响因素。方法 横断面调查获得2007-2015年沈阳市艾滋病治疗定点医院（中国医科大学附属第一医院）15-30岁学生HIV/AIDS患者ART相关信息，多因素logistic回归模型探讨ART的影响因素。结果 2007-2015年该医院共收治15-30岁学生HIV/AIDS患者146例，占累计治疗HIV/AIDS患者的6.1%（146/2 379）。患者均为男性，男男性行为传播途径占93.2%（136/146），HIV延迟诊断率[诊断时CD4＋T淋巴细胞计数（CD4）≤ 350个/μl]为52.7%（77/146），患者中ART的构成比为67.1%（98/146）。多因素logistic回归分析显示，HIV诊断年份（aOR=1.21，95%CI：1.02-1.44）、年龄24-30岁（aOR=8.15，95%CI：1.46-45.52）和延迟诊断（aOR=2.22，95%CI：1.05-4.71）是学生HIV/AIDS患者ART的独立影响因素。结论 HIV诊断时间越晚、年龄越大及延迟诊断可能增加学生HIV/AIDS患者的ART比例。。Objective To investigate the risk factors on antiretroviral therapy （ART） among HIV/AIDS positive students in Shenyang. Methods A cross-sectional study was conducted among HIV/AIDS positive students aged between 15 and 30, in an HIV-treatment-designated hospital in Shenyang city, during 2007-2015. Data were analyzed by multivariate logistic regression mode to identify the risk factors related to ART. Results A total of 2 379 HIV/AIDS patients attended the hospital and 6.1% （146/2 379） of them were students, during 2007-2015. All of the HIV/AIDS positive students were males, with homosexual transmission accounted for 93.2% （136/146）. The overall rate on delayed diagnosis was 52.7% （77/146）, when at diagnosis of CD4＋ T lymphocyte counts ≤ 350 cells/μl. The proportion of ART was 67.1% （98/146）. Factors as：year that the HIV diagnosis was made （aOR=1.21, 95%CI：1.02-1.44）, age between 24-30 （compared with age below 18-year-old, aOR=8.15, 95%CI：1.46-45.52）, and delayed diagnosis （aOR=2.22, 95%CI：1.05-4.71）, appeared independently related to ART among HIV/AIDS positive students. Conclusions Factors as the year that HIV diagnosis was made, age and delayed diagnosis of the patients seemed to be at higher risk for ART among HIV/AIDS positive students

关 键 词：艾滋病病毒 抗病毒治疗 危险因素 学生 

分 类 号：R512.91[医药卫生—内科学]