纤支镜联合局部注射药物治疗对于支气管扩张合并感染的治疗效果及安全性评价  

Evaluation on Treatment Effect and Safety of Bronchofiberscope Combined with Local Injection Drug Treatment for Bronchiectasia and Infection

作　　者：张睿花[1] 

机构地区：[1]吉林省人民医院呼吸科,吉林长春130021

出　　处：《系统医学》2017年第4期74-76,共3页Systems Medicine

摘　　要：目的探讨经纤维支气管镜联合局部注射药物治疗支气管扩张合并感染的治疗效果极其安全性。方法分析该院自2013年1月—2016年1月间收治的90例反复发作的老年支气管扩张合并感染患者,采用数字随机分组方法将其分为观察组以及对照组,每组45例,其中观察组给予纤支镜联合局部注射药物治疗,对照组应用常规疗法,比较两组症状缓解时间、住院时间、费用,治疗效果治疗前后的血气分析指标变化情况。结果观察组患者退热时间,咳嗽、咳痰消失时间以及湿罗音消失时间均明显低于对照组,观察组住院时间及总住院费用均明显低于对照组,观察组的治疗有效率为100.00%(45/45),对照组为84.44%(38/45),组间比较差异有统计学意义(P<0.05),治疗前两组患者的血气指标分析比较差异无统计学意义(P>0.05),治疗后对照组中PaO_2、SaO_2、PaO_2/FiO_2分别为(79.54±5.82)mm Hg、(90.79±3.59)%、(241.98±17.63),观察组分别为(83.09±4.26)mm Hg、(92.45±3.02)%、(252.78±12.87),均较治疗前好转,且组间比较差异有统计学意义(P<0.05)。结论采用纤支镜联合局部注射药物治疗支气管扩张合并感染能够发挥较好的治疗效果,缩短住院时间,减少住院费用,值得临床推广应用。Objective To study the treatment effect and safety of bronehofiberscope combined with local injection drug treatment for bronchiectasia and infection. Methods 90 cases of senile patients with bronchiectasia and infection admitted and treated in our hospital from January 2013 to January 2016 were analyzed, and randomly divided into two groups with 45 cases in each, the observation group were given the bronchofiberscope combined with local injection drug treatment, the control group were given the routine therapy, and the symptoms relief time, length of stay, cost, treatment effect and blood gas analysis indicator changes were compared between the two groups. Results The defervescence time, cough, expectoration disappearance time and moist rates disappearance time in the observation group were obviously lower than those in the control group, and the length of stay and total hospitalization cost in the observation group were lower than those in the control group, and the difference in the treatment effective rate between the observation group and the control group had no statistical significance [100.00%（45/45） vs 84.44%（38/45）], and the difference in the blood gas index analysis between the two groups before treatment had no statistical significance （P〉0.05）, and the differences in the PaO2,SaO2,PaO2/CFiO2 between the control group and the observation group after treatment had statistical significance [（79.54±5.82）mmHg,（90.79±3.59）%,（241.98±17.63） vs （83.09±4.26）mmHg,（92.45±3.02）%,（252.78 ±12.87）] （P〈0.05）. Conclusion The bronchofiberscope combined with local injection drug treatment for bronchiectasia and infection can give play to the better treatment effect, shorten the length of stay and reduce the hospitalization cost, which is worth clinical promotion and application in clinic.

关 键 词：纤支镜 局部注射 药物 支气管扩张 感染 

分 类 号：R562.22[医药卫生—呼吸系统]