针刺调周法治疗多囊卵巢综合征的临床疗效分析  

Effect of polycystic ovary syndrome treated with the periodic therapy of acupuncture

作　　者：杨丹红[1] 赵美 谈佳红 

机构地区：[1]浙江中医药大学附属第三医院针灸科,杭州310053 [2]温州市中西医结合医院针灸科 [3]湖州市南浔区中西医结合医院针灸科

出　　处：《中国针灸》2017年第8期825-829,共5页Chinese Acupuncture & Moxibustion

摘　　要：目的:初步观察针刺调周法与达因-35治疗多囊卵巢综合征(PCOS)的临床疗效差异并探讨其作用机制。方法:将60例患者随机分为针刺组和西药组,每组30例,两组各脱失1例,最终各纳入29例。针刺组予以针刺调周法治疗,以双侧三阴交、大赫、归来、关元、中极为主穴,同侧大赫、归来穴接电针(疏密波,2 Hz/100 Hz),于经后期、经间期、经前期辅以不同配穴,行经期若无不适可暂停治疗,每2 d治疗1次,每周治疗3次。西药组服用达因-35,每日1片,21 d为一疗程,疗程间休息7 d。两组均于月经周期第5 d开始治疗,连续治疗3个月。观察两组治疗前后月经周期、痤疮评分、体质量指数(BMI)及血清卵泡生成激素(follicle stimulating hormone,FSH)、黄体生成激素(luteinizing hormone,LH)、黄体生成激素与卵泡生成激素比值(LH/FSH)、睾酮(testosterone,T)水平变化情况,并比较两组疗效。结果:针刺组和西药组总有效率分别为75.9%(22/29)、79.3%(23/29),差异无统计学意义(P>0.05)。治疗后两组月经周期均短于治疗前(均P<0.05),且针刺组优于西药组(P<0.05),针刺组治疗前后差值大于西药组(P<0.05)。针刺组治疗后BMI明显低于治疗前(P<0.05),且低于对照组(P<0.01),针刺组治疗前后差值大于对照组(P<0.05)。两组痤疮评分均低于治疗前(均P<0.05),但治疗后组间差异无统计学意义(P>0.05)。两组治疗后FSH值均高于治疗前(均P<0.05),LH、LH/FSH以及T值均低于治疗前(均P<0.05),西药组T值低于针刺组(P<0.05),且西药组T值治疗前后差值大于针刺组(P<0.05)。结论:针刺调周法可能是治疗PCOS的优势疗法之一,能有效改善患者临床症状、部分激素水平和月经周期。Objective To observe the effects differences for polycystic ovary syndrome（PCOS） between periodic therapy of acupuncture and diane-35 and to explore its mechanism. Methods Sixty patients were randomly assigned into an acupuncture group and a western medication group, 30 cases in each one, 29 patients finally included with one case dropping out respectively. In the acupuncture group, periodic therapy was mainly used at bilateral Sanyinjiao（SP 6）, Dahe（KI 12）,Guilai（ST 29）, Guanyuan（CV 4）, Zhongji（CV 3）, with different acupoints in the postmenstrual, intermenstrual, premenstrual periods, once every other day, 3 times a week. EA（2 Hz/100 Hz） was used at bilateral Dahe（KI 12） and Guilai（ST 29）. If there was no discomfort during menstrual period, no treatment was given. In the western medication group, diane-35 was prescribed orally for 21 days as a course, with 7 days at interval, one tablet a day. All the treatment was started on the fifth day of the menstrual circle, for continuously 3 months. The indexes were observed before and after treatment, including the menstrual circle, acne score, body mass index（BMI）, serum follicle stimulating hormone（FSH）, luteinizing hormone（LH）,LH/FSH and testosterone（T）. The effects of the two groups were compared. Results The total effective rate was 75.9%（22/29） in the acupuncture group, which was not significantly different from 79.3%（23/29） in the western medication group（P〈0.05）. The menstrual cycles were shorter after treatment in the two groups（both P〈0.05）, with better effect and different value before and after treatment in the acupuncture group（both P〈0.05）. BMI in the acupuncture group after treatment was lower than that before treatment（P〈0.05） and that after treatment in the western medicine group（P〈0.01）, with better different value before and after treatment in the acupuncture group（P〈0.05）. The acne scores after treatment decreased in the two groups（both P〈0.05）, with

关 键 词：多囊卵巢综合征 针刺 调周法 随机对照试验 

分 类 号：R246.3[医药卫生—针灸推拿学]