青岛地区肺结核危险因素研究  

Study on risk factors of pulmonary tuberculosis in Qingdao

作　　者：朱可[1] 董梅[1] 陈晓光[1] 滕新栋 张娟[1] 张瑾[1] 徐颖[1] 

机构地区：[1]山东国际旅行卫生保健中心,山东青岛266001

出　　处：《中国国境卫生检疫杂志》2017年第3期164-166,共3页Chinese Journal of Frontier Health and Quarantine

基　　金：国家质检总局科技计划项目(2016IK197);山东出入境检验检疫局科技计划项目(SK201622)

摘　　要：目的了解青岛地区肺结核发生的危险因素,为制定科学的结核病监测措施提供基础。方法采用1∶1配比病例对照研究,对青岛地区2014年登记的328例涂阳肺结核患者和健康人群进行问卷调查,采用单因素和多因素条件logistic回归对发病危险因素进行分析。结果青岛地区肺结核患者中,20~40岁男性比例较大;单因素分析结果显示结核病病史、结核病患者接触史、吸烟史与肺结核的发生有显著联系(OR=19.500,7.556,1.468;P<0.05)。多因素分析结果显示结核病病史、结核病患者接触史是肺结核发生的危险因素(OR=18.573,7.693;P<0.001)。结论加强对既往有结核病史者、结核病接触者的管理工作,将有助于降低青岛地区结核病的流行强度。Objective To explore the risk factors of pulmonary tuberculosis（TB） in Qingdao,in order to provide scientific basis for the surveillance and prevention of TB. Methods Pair matched case-control study was conducted.A total of 328 sputum smear positive TB patients in Qingdao city were selected as case group in 2014,the health people from the same community were selected as control group. Questionnaire interview was conducted in all the subjects. Single variable and multiple variable conditional 1ogistic regression modeling were applied for data analysis.Results Single variable conditional analysis showed that TB history,smoking and history of exposure to TB were significant associated with incidence of TB（OR=19.500,7.556,1.468;P 〈0.05）,multivariable logistic regression analysis turned out that TB history and history of exposure to TB were the risk factors of TB in Qingdao city（OR=18.573,7.693;P〈 0.001）. Conclusion The control programs targeting those ever had TB patients and contacts to TB patients should be strengthened.

关 键 词：肺结核 危险因素 对照研究 LOGISTIC回归分析 

分 类 号：R181.34[医药卫生—流行病学]