现代名老中医诊治支气管哮喘文献证候分析  

Literature Research on Syndrome Characteristics of Bronchial Asthma based on Clinical Experiences of Contemporary Famous Chinese Medicine Physicians

作　　者：李宣霖[1] 马锦地 李建生[1] 王佳佳[1] 孙曙明[1] 李庆磊[1] 蔡永敏[1] LI Xuanlin MA Jindi LI Jiansheng WANG Jiajia SUN Shuming LI Qinglei CAI Yongmin(Henan University of Chinese Medicine/Henan Collaborative Innovation Centre for Diagnosis and Treatment of Respiratory Diseases and New Drug Development, Zhengzhou, 45004)

机构地区：[1]河南中医药大学/呼吸疾病诊疗与新药研发河南省协同创新中心

出　　处：《中医杂志》2017年第16期1416-1420,共5页Journal of Traditional Chinese Medicine

基　　金："十二五"国家科技支撑计划(2014BAI10B06);国家自然科学基金(81473648;81674098);河南省中医临床学科领军人才培育计划(HNZYLJ201301001);2015年河南省优势特色学科建设项目

摘　　要：目的基于现代名老中医诊治支气管哮喘的文献,对支气管哮喘常见证候及其临床特征进行分析,为支气管哮喘临床辨治提供依据。方法检索现代名老中医肺病数据库、期刊中医肺病数据库,筛选名老中医诊治支气管哮喘文献,采用频数、因子分析与聚类分析、二元Logistic回归分析等方法对支气管哮喘症状、证型进行分析。结果检索出符合纳入标准的文献2459篇,频率≥3.0%的证型包括痰热壅肺证、痰湿阻肺证、寒饮停肺证、风寒袭肺证、肺脾气虚证、肺肾阳虚证、肺肾气虚证、肾气虚证、肺气虚证、寒痰阻肺证、肺气阴两虚证。对症状进行因子分析及聚类分析,得到5类较有意义的症状聚类组合,结果结合临床实际,总结出支气管哮喘的常见证候有痰热壅肺证、风寒袭肺证、肺脾气虚证、肺气虚证、肺气阴两虚证,并分别得到各证候的主症、次症。结论支气管哮喘的临床常见证候有痰热壅肺证、风寒袭肺证、肺脾气虚证、肺气虚证、肺气阴两虚证,每个证候均有症状特异性。Objective Based on literature of experiences of contemporary famous Chinese medicine physicians in the diagnosis and treatment of bronchial asthma to analyze the common syndromes and the clinical features of bronchial asthma to provide basis for clinical differentiation and treatment. Methods Database of Experiences of Contemporary Famous Chinese Medicine Doctors in Treatment of Lung Disease and Database of Journal Articles on Chinese Medicine for Lung Disease were searched and the papers on diagnosis and treatment of bronchial asthma by famous Chinese medicine doctors were screened. The symptoms and syndrome types of bronchial asthma were analyzed with the methods of frequency-factor analysis,cluster analysis and two element Logistic regression analysis. Results Totally 2459 papers met inclusion criteria were found out from the databases. Syndromes with the frequency ≥3. 0% were syndrome of phlegm-heat congesting lung,syndrome of phlegm-dampness blocking lung,syndrome of cold fluid retained in lung,syndrome of wind-cold attacking lung,syndrome of Qi deficiency of lung and spleen,syndrome of Yang deficiency of lung and kidney,syndrome of Qi deficiency of lung and kidney,syndrome of kidney-qi deficiency,syndrome of lung-qi deficiency,syndrome of cold-phlegm obstructing lung,and syndrome of deficiency of both Qi and Yin of lung. Factor analysis and cluster analysis were made on symptoms. Five meaningful symptom clustering combinations were obtained. Combined with clinical practice,the authors summarized that common syndromes of bronchial asthma were syndrome of phlegm-heat congesting lung,syndrome of wind-cold attacking lung,syndrome of Qi deficiency of lung and spleen,syndrome of lung-qi deficiency,and syndrome of deficiency of both Qi and Yin of lung.Main symptoms and secondary symptoms of each syndrome were obtained. Conclusion Clinically,the common syndromes of bronchial asthma are syndrome of phlegm-heat congesting lung,syndrome of wind-cold attacking lung,syndrome of Qi deficiency of lung and spleen,syndrom

关 键 词：支气管哮喘 证候 名老中医经验 文献研究 

分 类 号：R256.12[医药卫生—中医内科学]