珠海市2010至2015年围产儿先天性心脏病监测分析  

Monitoring results of congenital heart disease of perinatal infants in Zhuhai City from 2010 to 2015

作　　者：黄斯娜[1] 赵静[1] HUANG Si-na ZHAO Jing(Zhuhai Maternity and Child Health Care Hospital, Guangdong Zhuhai 510000, China)

机构地区：[1]广东省珠海市妇幼保健院,广东珠海510000

出　　处：《中国妇幼健康研究》2017年第7期812-814,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的分析珠海市2010至2015年围产儿先天性心脏病的发生情况,为制定预防干预策略提供依据。方法对珠海市2010年1月1日至2015年12月31日出生缺陷监测中围产儿先天性心脏病资料进行回顾性分析。结果珠海市2010至2015年围产儿先天性心脏病平均发生率为52.11/万,呈逐年上升趋势(χ~2=2 296 751.99,P<0.01);合并其他类型出生畸形占8.65%(78/902),以染色体异常、肾脏畸形为主;动脉导管未闭、房间隔缺损、室间隔缺损、法络氏四联症、大动脉转位分列先天性心脏病分类前五位;产前诊断率占9.53%(86/902);不同患儿性别、常住地、母亲年龄段间的先天性心脏病发病率差异均有统计学意义(χ~2值分别为9.49、9.74、14.30,均P<0.05)。结论 2010至2015年珠海市围产儿先天性心脏病发病率持续上升;利用已完善的妇幼保健网络,广泛持久开展相关健康教育,提高产前诊断水平,加强新生儿保健,有助于降低围产儿先天性心脏病的发病率。Objective To analyze the occurrence of congenital heart disease（CHD） of perinatal infants in Zhuhai City from 2010 to 2015 so as to provide evidence for taking preventive measures. Methods Retrospective study was conducted on CHD in birth defects surveillance data in Zhuhai City from January 1,2010 to December 31,2015. Results The total incidence of CHD of perinatal infants was 52. 11/10000,showing an increasing trend（ χ2= 2 296 751. 99,P〈 0. 01）. Cases with CHD combining other deformities occupied 8. 65%（ 78/902）,and chromosome abnormity and renal malformation were the major ones. The top five types of CHD were patent ductus arteriosus,atrial septal defect,ventricular septal defect,tetralogy of Fallot and transposition of great arteries. The prenatal diagnostic rate of CHD was9. 53%（86/902）. There were significant differences in the incidence of CHD among cases of different genders,at different residential address and different maternal age（ χ2value was 9. 49,9. 74 and 14. 30,respectively,all P〈 0. 05）. Conclusion The incidence rate of CHD in Zhuhai City increases rapidly from 2010 to 2015. Enhancing health education extensively,improving prenatal diagnostic ability and reinforcing newborn care are helpful to reduce the incidence rate of CHD of perinatal infants.

关 键 词：先天性心脏病 监测 发生率 围产儿 

分 类 号：R725.4[医药卫生—儿科]