Enthalpy of phase transition of isonicotinic acid  

作　　者：Dongfang Zhao Guanghui Liu Jian Sun Lisheng Wang 

机构地区：[1]School of Chemical Engineering and Environment,Beijing Institute of Technology,Belting 100081,China

出　　处：《Chinese Journal of Chemical Engineering》2017年第7期971-975,共5页中国化学工程学报（英文版）

摘　　要：In this work, the group contribution method of Chickos et al. was applied to estimate the fusion enthalpy of isonicotinic acid, and the obtained result(29.2 k J·mol^(-1)) showed a large difference with the value(135 k J·mol^(-1)) as reported from literatures and as determined by differential scanning calorimetry(DSC). The results of DSC/TG measurement showed that the phase transition of isonicotinic acid from 187.27 °C to277.47 °C underwent a sublimation process, with a sublimation enthalpy of 128.03 k J·mol^(-1). An efficient analytical technique combining pyrolysis and gas chromatography/mass spectrometry(Py-GC/MS) was used to prove this conclusion.In this work, the group contribution method of Chickos et al. was applied to estimate the fusion enthalpy of isonicotinic acid, and the obtained result（29.2 k J·mol^-1） showed a large difference with the value（135 k J·mol^-1） as reported from literatures and as determined by differential scanning calorimetry（DSC）. The results of DSC/TG measurement showed that the phase transition of isonicotinic acid from 187.27 °C to277.47 °C underwent a sublimation process, with a sublimation enthalpy of 128.03 k J·mol^-1. An efficient analytical technique combining pyrolysis and gas chromatography/mass spectrometry（Py-GC/MS） was used to prove this conclusion.

关 键 词：lsonicotinic acid Enthalpy of fusion Group contribution method Enthalpy of sublimation Py-GC/MS 

分 类 号：O626.32[理学—有机化学]