早期支气管镜肺泡灌洗对支气管扩张合并感染患者的影响  

Effects of early bronchoalveolar lavage through bronchoscope in bronchiectasis with infection

作　　者：黎艳聪[1] 郭超文[1] 张杰斯 袁健志 Li Yaneong et al(Xiaolan People＇s Hospital Affiliated to the Southern Medical University, Zhongshan 528415, China)

机构地区：[1]南方医科大学附属小榄人民医院,广东528415

出　　处：《齐齐哈尔医学院学报》2017年第12期1386-1389,共4页Journal of Qiqihar Medical University

摘　　要：目的探讨早期纤维支气管镜肺泡灌洗对支气管扩张合并感染患者的影响。方法将我院2015年1月至2016年6月收治的70例诊断明确的支气管扩张合并感染患者随机分为观察组和对照组,每组35例。对照组予应用祛痰药物、拍背排痰、全身应用抗菌药和维持水电解质平衡、营养支持等常规治疗;观察组在上述常规治疗的基础上实行早期支气管镜肺泡灌洗的方法。观察两组患者治疗前后的一般指标(体温、呼吸频率、脉搏)、血常规及血清降钙素原和细菌检出率,并对比两组的抗生素使用时间及平均住院时间、3个月内再入院率等指标。结果治疗后两组体温、呼吸频率、脉搏比较,均低于治疗前,但观察组患者上述指标改善更为明显(P<0.05);治疗后两组的白细胞及血清降钙素原水平均低于治疗前,观察组较对照组下降得更为明显,差异有统计学意义(P<0.05);观察组的细菌检出率为57.1%,对照组为28.6%,差异有统计学意义(P<0.05);观察组平均抗生素使用天数、平均住院天数、3个月内再入院率分别为(6.8±2.2)d、(8.9±3.1)d、5.71%,而对照组为(11.5±2.6)d、(15.6±3.5)d、14.29%,差异具有统计学意义(P<0.05)。结论早期支气管肺泡灌洗能有效改善支气管扩张合并感染患者一般生命指标,提高患者的细菌检出率,且大大缩短了抗生素的使用时间,平均住院日,并降低了再入院率,有较高的临床应用价值,值得临床推广。Objective To observe the effects of early bronchoalveolar lavage through bronchoscope in bronchiectasis with infection. Methods This research included 70 aspiration pneumonia cases from Xiaolan People＇s Hospital Affiliated to the Southern Medical University during January,2015 to June,2016. They were separated into observed group and control group randomly. Patients in the control group were given usualtreatments,like expectorant medicine; slap treatment,systemic administration of antibiotics,electrolyte balance maintenance and nutritional support. Patients in the observed group were given usual treatments and early bronchoalveolar lavage through bronchoscope. The data of temperatures,respiration rates,pulses,the number of white blood cell,and the blood level of procalcitonin were gathered. Also the bacteria detection rates,the days of antibiotic use,the hospital stays and readmission within 3 months were marked. Results After treatment,lower temperatures,respiration rates and pulses had been found than before in both groups. The change of observed group was more significant than that of control group（ P〈0.05）. Less white blood cells and lower blood level of procalcitonin than before had been found treatment in both groups,while the change of the observed group was more obvious（ P〈0.05）. The bacteria detection rate of observed group was 87. 78%,control group,42. 42%.There was a significant difference（ P〈0.05）. The observed group used antibiotics for（ 6. 8 ± 2. 2） days,control group,（ 11.5±2.6） days. There was a significant difference（ P〈0.05）. The hospital stay of the observe group was（ 8.9±3.1） days,control group,（ 25.6±3.5） days. There was a significant difference（ P〈0.05）. The readmission within 3 months of observed group was 5. 7%,control group,14. 3%,There was a significant difference（ P〈0.05）. Conclusions Early bronchoalveolar lavage through bronchoscope in patients with bronchietasis with infection can help to improve general life index,improve bact

关 键 词：支气管扩张合并感染 纤维支气管镜 肺泡灌洗 早期 

分 类 号：R56[医药卫生—呼吸系统]