Detection of dopamine at graphene-ZIF-8 nanocomposite modified electrode  

作　　者：Yan-Yan Zheng Chang-Xia Li Xiao-Teng Ding Qi Yang Ya-Min Qi Hui-Min Zhang Liang-Ti Qu 

机构地区：[1]School of Chemistry and Chemical Engineering,Beijing Institute of Technology,Beijing 100081,China

出　　处：《Chinese Chemical Letters》2017年第7期1473-1478,共6页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(Nos.21575014 and 21175013)

摘　　要：A hybrid graphene-ZIF-8（G-ZIF-8） nanocomposite modified electrode was prepared in our work. SEM characterization shows that nanocrystals of zeolitic imidazolate frameworks（ZIF-8） were homogeneously well-intergrown on the surface of graphene and thus the graphene sheets were refrained from restacking, which implies the high accessible surface area. The BET results further testifies that G-ZIF-8composites had a larger surface area than 3D graphene. G-ZIF-8 modified electrode exhibited excellent electroanalytical performance for dopamine. The linear concentration range was from 3.0 mmol/L to1.0 mmol/L with the detection sensitivity of 0.34 m A/mmol/L and the detection limit of 1.0 mmol/L was obtained. The interference study, electrode stability and reproducibility were carried out. In addition, the prepared sensor was applied to the detection of DA in serum sample with recoveries from 96.8% to100.7%. It is believable that the structure characteristic of G-ZIF-8 nanocomposite is favorable for using MOFs to fabricate highly sensitive electrochemical sensorA hybrid graphene-ZIF-8（G-ZIF-8） nanocomposite modified electrode was prepared in our work. SEM characterization shows that nanocrystals of zeolitic imidazolate frameworks（ZIF-8） were homogeneously well-intergrown on the surface of graphene and thus the graphene sheets were refrained from restacking, which implies the high accessible surface area. The BET results further testifies that G-ZIF-8composites had a larger surface area than 3D graphene. G-ZIF-8 modified electrode exhibited excellent electroanalytical performance for dopamine. The linear concentration range was from 3.0 mmol/L to1.0 mmol/L with the detection sensitivity of 0.34 m A/mmol/L and the detection limit of 1.0 mmol/L was obtained. The interference study, electrode stability and reproducibility were carried out. In addition, the prepared sensor was applied to the detection of DA in serum sample with recoveries from 96.8% to100.7%. It is believable that the structure characteristic of G-ZIF-8 nanocomposite is favorable for using MOFs to fabricate highly sensitive electrochemical sensor

关 键 词：ZIF-8 Graphene Nanocomposite Modified electrode Dopamine 

分 类 号：O657.1[理学—分析化学] TB383[理学—化学]