脉冲振荡肺功能在矽肺病患者早期诊断及随访中的意义  

Significance of pulsed pulmonary function in early diagnosis and follow-up of patients with silicosis

作　　者：陈伟文[1] 郭伟峰[1] 李萌[1] 沈冰寒[1] 李翠梅[1] 王志刚[1] 

机构地区：[1]福建医科大学附属泉州第一医院重症医学科、呼吸内科,福建省泉州市362000

出　　处：《临床合理用药杂志》2017年第22期33-34,共2页Chinese Journal of Clinical Rational Drug Use

基　　金：脉冲振荡肺功能在矽肺病患者早期诊断及随访中的意义(No:FZS13028Y计划文号:医大科技【2013】37号)

摘　　要：目的分析脉冲振荡技术(IOS)用于矽肺病患者肺功能早期诊断及随访中的价值。方法对连续接触3年以上硅粉尘且经螺旋CT扫描诊断并确诊为矽肺病患者90例进行IOS检测,并与常规通气功能检测结果进行对比,比较不同分期矽肺病患者的IOS指标情况。结果 IOS检测总阳性率为91.11%,常规通气检测患者的总阳性率为78.89%,差异有统计学意义(P<0.05);Ⅲ期矽肺患者的Fres和R5-R20等指标情况显著高于Ⅰ期和Ⅱ期矽肺病患者,X5指标显著低于Ⅰ期、Ⅱ期患者,差异均有统计学意义(P<0.05)。结论采用IOS诊断早期矽肺病患者具有较高的阳性率,有助于患者的早期诊断,同时可反映患者的病变程度。Objective To analyze the value of pulsed oscillatory technique（IOS） in early diagnosis and follow-up of pulmonary function in patients with silicosis.Methods 90 cases of continuous diagnosis of silicosis were measured and compared with the results of conventional ventilation test,and the IOS indexes of patients with silicosis were compared with those of the patients with silicosis.Results The positive rate of IOS（91.11%） was higher than that in patients with conventional ventilation（78.89%）,the difference was statistically significant（P〈0.05）.Fres and R5-R20 were significantly higher in patients with stage Ⅲ silicosis than those of stage ⅠandⅡsilicosis,while X5 The index was significantly lower than that of stageⅠandⅡ,the differences were statistically significant（P〈0.05）.Conclusion The use of IOS diagnosis of early silicosis patients with a high positive rate,help patients with early diagnosis,and can reflect the degree of disease in patients.

关 键 词：肺功能检测 矽肺病 脉冲振荡技术 

分 类 号：R135.2[医药卫生—劳动卫生]