16101例门急诊患者注射用头孢菌素类药物的使用及其皮试结果分析  

Analysis on Medication and Results of Skin Sensitive Test of Cephalosporins for Injections in 16101 Out-patients

作　　者：金炎[1] 邹金花[1] 

机构地区：[1]苏州市中医医院药学部,江苏苏州215009

出　　处：《抗感染药学》2017年第4期736-738,共3页Anti-infection Pharmacy

摘　　要：目的:分析医院门急诊患者注射用头孢菌素类药物的使用及其皮肤敏感试验(以下简称皮试)结果,为临床安全用药提供参考。方法:选取2015年1—12月间门急诊接受注射用头孢菌素类药物治疗的患者16101例,拟用药物原液皮试结果示阳性的,分析其皮试阳性结果的原因。结果:16101例患者中皮试结果示阳性的414例占2.57%;金额排序/DDDs排序的序号比>1的药物占85.70%;皮试阳性率与DDDs的相关系数为0.690(P>0.05)。结论:门急诊患者头孢菌素类注射剂的使用是合理的,各头孢菌素类注射剂皮试阳性率间均存在差异性,因此用药前有必要采用其原液皮试,以避免严重不良反应的发生。Objective： To analyze the medication and results of skin sensitive test of cephalosporins for injections in 16 101 out-patients, and to provide a reference for clinical safe medication. Methods： Selecting out-patients from our hospital during 2015 January to December in outpatient and emergency treatment of cephalosporins for injection, the drug should be used for skin test; if the results were positive, the reasons of the test positive result was analyzed. Results： The positive 414 cases had received the skin test in 16 101 patients, its positive rate was 2.57%. The amount of sorting/DDDs ranking number ratio of more than 1 drugs accounted for 85.7%; the correlation coefficient and DDDs skin test positive rate were 0.690 with no statistical significance （P〉0.05）. Conclusion： The medication of cephalosporins for injection in out-patient is reasonable, and there was a difference between the positive rates of the skin test positive rate ofcephalospotins. So it is necessary to take the liquid skin test before taking the drug,and to avoid severe adverse reactions.

关 键 词：头孢菌素类 头孢菌素溶液 皮试阳性 

分 类 号：R969.3[医药卫生—药理学]