硫唑嘌呤治疗视神经脊髓炎谱系病致1例粒细胞缺乏的分析  

Analysis on One Case of Azathioprine-induced Agranulocytosis in Patients with Neuromyelitis Optica Spectrum Disorders

作　　者：王蒙蒙[1] 许静[1] 马春来[2] 

机构地区：[1]南京医科大学附属儿童医院药剂科,南京210008 [2]复旦大学附属华山医院药剂科,上海200040

出　　处：《药学与临床研究》2017年第4期363-365,共3页Pharmaceutical and Clinical Research

摘　　要：对硫唑嘌呤治疗视神经脊髓炎谱系病(NMOSD)致1例粒细胞缺乏进行分析,从硫唑嘌呤致造血系统损害的临床特点、发生率、不良反应预防、基因多态性以及NMOSD患者粒细胞缺乏的治疗措施等方面进行分析和讨论,为临床有效、安全用药提供参考。One case of agranulocytosis induced by taking azathioprine for neuromyelitis optica spectrum disorders （NMOSD） was reported. And it was analyzed retrospectively in terms of clinical characteristics, incidence rate, precautionary measures of the adverse reactions, gene polymorphism and treatment of agranulocytosis for NMOSD patients, which may provide reference for effective and safe use of drugs in clinic.

关 键 词：硫唑嘌呤 视神经脊髓炎谱系病 造血系统损害 重组人粒细胞集落刺激因子 

分 类 号：R969.3[医药卫生—药理学]