2010-2016年南京市发热伴血小板减少综合征流行特征分析  

Epidemiological characteristics of severe fever with thrombocytopenia syndrome in Nanjing,China from 2010 to 2016

作　　者：马涛[1] 徐庆[1] 李晨[1] 张钟[1] 丰罗菊[1] 李伟[1] 许阳婷[1] 随海田[2] 洪镭[1] 

机构地区：[1]江苏省南京市疾病预防控制中心,江苏南京210003 [2]中国疾病预防控制中心卫生应急中心,北京102206

出　　处：《现代预防医学》2017年第16期2890-2894,共5页Modern Preventive Medicine

摘　　要：目的了解南京市发热伴血小板减少综合征(SFTS)的流行病学特征,为制定有效的防控策略和措施提供科学依据。方法采用描述流行病学方法,分析2010-2016年南京市报告的SFTS病例时间、人群、地区分布特征和报病医疗机构分布等,并将2016年流行特征与2010-2015年进行比较。结果 2010-2016年南京市共报告SFTS确诊病例70例,年均10例(2~30例),年均报告发病率为0.14/10万(0.05/10万~0.36/10万)。4-11月有病例报告,5-7月是主要发病高峰(63%)。男性占56%,病例年龄中位数为60岁(26~82岁),男女年龄分布位置相同(P=0.82);病例以农民为主(63%),其次是家务及待业(20%)。报告病例数前三位地区为溧水区(39%)、江宁区(19%)、浦口区(14%),共占报告病例数的71%。2010年报告一起家庭聚集性疫情,发现3例病例,血液、分泌物或排泄物可能是重要传播因子。全市共有9家机构报告SFTS病例,其中3家三级综合性医疗机构报告了全市84%的病例,病例发病至诊断时间间隔中位数为10d(0~30 d)。结论 2016年南京市报告SFTS病例显著增加,流行特征与2010-2015年一致,应进一步采取综合措施防控SFTS。Objective The aim of this study was to investigate the epidemiological characteristics of severe fever with thromboeytopenia syndrome （SFTS） in Nanjing, China from 2010 to 2016, for developing the prevention and control strategy. Methods Descriptive epidemiological method was conducted to analyze epidemio]ogical characteristics of the collected SFIS reported data of Nanjing from January 1, 2010 to December 31, 2016, through the National Notifiable Infectious Disease Surveillance System. The time, area, population distribution, and reporting medical institutions of SFTS cases were analyzed. Comparison between epidemiological characteristics between 2016 and the period from 2010 to 2015 was conducted. Results A total of 70 SFTS cases were reported in Nanjing during the period from 2010 to 2016. The average annual number was 10 （2-30） and the annual incidence was 0.14/100 000 （ranged from 0.05/100 000 to 0.36/100 000）. The cases were reported from April to November and the incidence peaked in May to July （63%）. The number of male cases accounted for 56%. The median age was 60 （ranged from 26 to 82）, and the age distribution of both genders was the same （/9=0.82）. Farmers accounted for 63% of the reported cases, followed by the people involved in housekeeping and job losing （20%）. The case numbers reported in Lishui （39%）, Jiangning （19%） and Pukou （14%） districts accounted for 71%. A family cluster outbreak was reported in 2010 and 3 cases were detected. The significant transmission factors might be blood, secretion or excretion. A total of 9 medical institutions in Nanjing reported SFTS cases, and 3 comprehensive medical institutions reported 84% of the cases. The median time interval from onset to diagnosis was 10 d （0~30d）. Conclusion The reported SFTS cases in Nanjing increased significantly in 2016, showing a same epidemiological feature with that from 2010 to 2015. Comprehensive measures should be taken for prevention and control.

关 键 词：布尼亚病毒 发热伴血小板减少综合征 流行病学特征 新发传染病 

分 类 号：R181.2[医药卫生—流行病学]