民航飞行人员高尿酸血症的现状调查  

The present status of hyperuricemia in civil aviation flying personnel

作　　者：郑晓艳[1] 

机构地区：[1]中国民航飞行学院医院,四川省广汉618307

出　　处：《中华航空航天医学杂志》2017年第1期23-28,共6页Chinese Journal of Aerospace Medicine

摘　　要：目的通过调查民航飞行学院飞行人员尿酸水平及其与血脂、体质指数、腰围、高血压、脂肪肝、糖尿病、泌尿系结石等的关系，分析高尿酸血症的危险因素，探讨飞行人员尿酸水平应控制的范围及其防治措施。方法采用回顾性分析方法，对中国民航飞行学院1721名飞行人员年度体检资料进行分析。根据尿酸水平进行分组，比较尿酸正常组与高尿酸血症组之间血脂水平、体质指数、腰围的差异，以及两组高血压病、糖尿病、肾结石、脂肪肝患病率的差异。对尿酸的相关影响因素进行非条件Logistic回归分析。结果在参加年度体检的1721名飞行人员中，高尿酸血症患病率为25．10％。与尿酸正常组比较高尿酸血症组体质指数、腰围增大，甘油三酯、胆固醇、LDL-C水平升高，HDL—C水平降低，差异有统计学意义（t=2．764-7．244，P〈0．01）。高尿酸血症组饮酒率、脂肪肝患病率高于正常组（χ^2=5．710、7．513，P〈0．05）。腹型肥胖、高脂血症、饮酒与民航飞行人员高尿酸血症显著相关（P〈0．05）。结论体质指数、腰围、血脂水平、饮酒、脂肪肝与高尿酸血症相关。腹型肥胖、高脂血症、饮酒是民航飞行人员高尿酸血症的主要危险因素。控制体重、降低血脂水平、禁酒可有效控制尿酸水平，必要时应降尿酸治疗。Objective To investigate the relationship between the level of blood uric acid and blood fat, body mass index （BMI）, waist circumference, blood pressure, fatty liver disease, diabetes, urinary calculi in flying personnel of Civil Aviation Flight University of China, to search for risk factors leading to hyperuricemia, and to discuss the normal range of blood uric acid of flying personnel and prevention measures. Methods The physical examination data of 1 721 flying personnel in Civil Aviation Flight University of China were analyzed through the retrospective analysis method. According to blood uric acid level, they were divided into two groups., hyperuricemia group and control group. The comparisons on the difference of blood fat, BMI, waist circumference, and on the prevalence of hypertension, diabetes, kidney stones, fatty liver were done between two groups. Effective factors of blood uric acid were analyzed with the non-conditional Logistic regression. Results In 1 721 examined flying personnel, prevalence rate of hyperuricemia was 25.10%. BMI and waist circumference in hyperuricemia group was respectively bigger than that of control group. The triglyceride, cholesterol and LDL-C level in hyperuricemia group was respectively higher than that of control group. HDL-C in hyperuricemia group was lower than that of control group （t=2. 764-7.24,P〈0.01） . The percentage of drinking and fatty liver prevalence in hyperuricemia group were higher than those in control group （χ^2 =5. 710, 7. 513, P〈0.05））. Abdominal obesity, hyperlipemia and drinking habit were significantly related to hyperurieemia （P〈0. 05）. Conclusions BMI, waist circumference, the level of blood fat, drinking habit and fatty liver are related to hyperuricemia. Abdominal obesity, hyperlipidemia and drinking habit are the main risk factors which cause hyperuricemia of civil flying personnel. The preventions such as controlling the weight and the level of blood fat, as well as banning drinking would be helpful to manage the level

关 键 词：高尿酸血症 危险因素 流行病学研究 飞行人员 

分 类 号：R85[医药卫生—航空、航天与航海医学]