HIV/艾滋病患者合并气胸的临床分析  

Pneumothorax in HIV/AIDS patients

作　　者：向攀[1] 赵红心[1] 

机构地区：[1]首都医科大学附属北京地坛医院重症医学科,感染病科国家临床重点专科,北京市中西医结合感染性疾病研究所,100015

出　　处：《中华全科医师杂志》2017年第8期624-627,共4页Chinese Journal of General Practitioners

摘　　要：回顾性分析2009年1月至2015年12月在首都医科大学附属北京地坛医院住院治疗的50例HIV/艾滋病（AIDS）合并气胸患者的临床资料.HIV/AIDS患者住院气胸的发生率为1.6％（50/3 177）,病死率52.0％ （26/50）;37例（37/50）患肺孢子菌肺炎（PCP）,是HIV/AIDS患者合并气胸的主要肺部疾病.以20例在重症内科部行机械通气后气胸的HIV/AIDS合并PCP患者为观察组,以同期未出现气胸的20例PCP患者为对照行多因素logistic回归分析,呼气末正压通气水平与HIV/AIDS合并PCP患者机械通气后气胸发生率呈正相关（P＜0.05,OR =2.49）.A total of 3 177 HIV/AIDS patients were admitted in Beijing Ditan Hospital,Capital Medical University from January 2009 to December 2015,among whom pneumothorax developed in 50 cases with a morbidity rate of 1.6%.Twenty six HIV/AIDS patients with pneumothorax died with a case fatality rate of 52.0% （26/50）.Pneunocystis jirovecii pneumonia （PCP） was the dominant lung disease related to pneumothorax （37/50）.Risk factors of pneumothorax were assessed among 40 HIV/AIDS patients with PCP undergoing mechanical ventilation in ICU,including 20 cases with pneumothorax and 20 cases without pneumothorac.Multivariate logistic regression analysis revealed that positive end-expiratory pressure （PEEP） was independent risk factor of pneumothorax in HIV/AIDS patients with PCP under mechanical ventilation （OR =2.490,95 % CI：1.302-4.763,P =0.01）.

关 键 词：HIV感染 获得性免疫缺陷综合征 气胸 肺炎 肺囊虫性 

分 类 号：R512.91[医药卫生—内科学]