孕妇生殖道感染对胎膜早破早产及妊娠结局影响的临床分析  

Influence of reproductive tract infections on premature rupture of membranes and outcomes of maternal and neonatal

作　　者：徐流立[1] 张琳[1] 祝参[1] 张豪[1] 杨霄[1] 郝丽霞[1] 

机构地区：[1]河南省安阳地区医院妇产科,河南安阳455000

出　　处：《中华医院感染学杂志》2017年第15期3555-3558,共4页Chinese Journal of Nosocomiology

摘　　要：目的探讨孕妇生殖道感染对胎膜早破早产以及妊娠结局的影响,为临床治疗提供参考依据。方法选取2014年6月-2015年5月期间医院收治的162例胎膜早破患者,根据是否合并孕期生殖道感染分为观察组84例与对照组78例,观察组给予相应治疗,统计有效率,并对比两组孕妇临床指标。结果观察组患者治愈率为46.43%,有效率为94.05%;观察组胎膜早破时间及分娩时间均显著早于对照组(P<0.05),妊娠延长时间显著短于对照组(P<0.05);观察组早产率、产褥病率、新生儿窒息发生率、新生儿感染率、胎盘绒毛膜羊膜炎发生率均显著高于对照组(P<0.05);新生儿出生体质量显著低于对照组(P<0.05),两组剖宫产发生率比较,差异无统计学差异。结论孕期生殖道感染可引起胎膜早破、早产,增加新生儿窒息发生率、新生儿感染率、胎盘绒毛膜羊膜炎的发生,严重影响妊娠结局,应加强预防,积极治疗,以保证母婴生命安全。OBJECTIVE To discuss the influence of reproductive tract infections on premature rupture of membranes（PROM）and outcomes of maternal and neonatal,so as to provide references for clinical treatment.METHODS A total of 162 pregnant women with PROM from Jun.2014 to May 2015 in Henan Anyang Hospital were selected,and were divided into observation group（n=84,with reproductive tract infection）and control group（n=78,without reproductive tract infection）.Patients in observation group were treated and the effective rate was calculated,and the clinical indexes between the two groups were compared.RESULTS The cure rate in observation group was 46.43% ,and the effective rate was 94.05% .The PROM time and delivery time in observation group were significantly earlier than those in control group（P〈0.05）,time of prolonged pregnancy in observation group was significantly shorter than that in control group（P〈0.05）,the premature delivery rate,puerperal morbidity,incidence of neonatal asphyxia,neonatal infection rate and incidence of chorioamnionitis in observation group were significantly higher than those in control group（P〈0.05）,birth weight of newborn in observation group was significantly lower than that in control group（P〈0.05）,and no significant difference in cesarean section rate between the two groups.CONCLUSIONReproductive tract infection during pregnancy can cause PROM and premature delivery,increase the incidence of neonatal asphyxia,neonatal infection rate,and chorioamnionitis,seriously affecting the outcome of pregnancy,so we should strengthen the prevention,active to therapy,so as to ensure the safety of mother and child.

关 键 词：生殖道感染 胎膜早破 妊娠结局 

分 类 号：R711.3[医药卫生—妇产科学]