基于Mn掺杂ZnS量子点室温磷光法检测盐酸巴马汀  

Detection of Palmatine Hydrochloride by Room Temperature Phosphorescence Method Based on Mn Doped ZnS Quantum Dots

作　　者：安昭琦 栗东霞[1] 于建敏[1] 闫桂琴[1] 

机构地区：[1]山西师范大学生命科学学院,山西临汾041000

出　　处：《分析科学学报》2017年第4期467-472,共6页Journal of Analytical Science

基　　金：国家自然科学基金(No.31272258);国家教育部博士点联合基金(No.20111404110002);山西省重点化学优势学科建设项目(No.912019)

摘　　要：本文以3-巯基丙酸(3-Mercaptopropionic Acid,MPA)为稳定剂,采用水相合成法制备了Mn掺杂ZnS量子点(Mn∶ZnS QDs),基于Mn∶ZnS QDs的室温磷光性质,盐酸巴马汀(Palmatine Hydrochloride,PaH)可与Mn∶ZnS QDs发生静电作用,使得Mn∶ZnS QDs发生室温磷光猝灭效应,从而发展了一种高效、快速检测人体体液中痕量PaH的新方法。实验结果表明,当PaH的浓度在0.75~30μmol/L范围时,其浓度与室温磷光猝灭强度(ΔIRTP)呈良好的线性关系,相关系数为0.996,检出限为0.35μmol/L,加标回收率为94.0%~103.3%。Mn doped ZnS quantum dots（QDs）were prepared through water phase synthesis method by taking 3-mercaptopropionic acid（MPA）as a stabilizer.Based on the room temperature phosphorescence of Mn doped ZnS QDs,electrostatic interaction was occurred between palmatine hydrochloride（PaH）and Mn doped ZnS QDs,resulting in the quenching effect of room temperature phosphorescence to Mn doped ZnS QDs.Therefore,an effective and rapid method was developed to detect trace PaH in human body fluid.When the PaH concentration was 0.75-30μmol/L,agood linear relationship was represented between it and phosphorescence quenching intensity（ΔIRTP）with the correlation coefficient of 0.996,and the detection limit and recovery is 0.35μmol/L and 94.0%-103.3%,respectively.

关 键 词：Mn掺杂ZnS量子点 室温磷光法 盐酸巴马汀 

分 类 号：O657.39[理学—分析化学]