基于石墨烯分子印迹电化学传感器测定芦丁  

Graphene Modified Molecularly Imprinted Electrochemical Sensor for Determination of Rutin

作　　者：谢丹[1] 龙立平[1] 刘蓉[1] 钟桐生[1] 李媛[1] 唐桥亭 

机构地区：[1]湖南城市学院材料与化学工程学院,湖南益阳413000

出　　处：《分析科学学报》2017年第4期545-548,共4页Journal of Analytical Science

基　　金：湖南省自然科学基金(No.2015JJ2023);黑茶金花湖南省重点实验室开放基金(No.2016TP1022);益阳市科技计划(益科字[2016]51号;湖南省教育厅高校科研一般项目(No.15C0244);湖南省高校科技创新团队支持计划(No.(2014)207号)

摘　　要：将石墨烯(GR)滴涂至裸Au电极表面,并以邻氨基酚为功能单体,芦丁为模板分子,制备了芦丁分子印迹膜电化学传感器,利用循环伏安法(CV)和差分脉冲伏安法(DPV)对制得的传感器进行了电化学性能研究,并且对制备条件和测定条件进行了优化。结果表明,与裸Au电极相比,该GR修饰的Au电极在[Fe(CN)_6]^(3-/4-)溶液中峰电流明显增大,显著提高了芦丁分子印迹传感器的灵敏度。在最优实验条件下,基于GR分子印迹电化学传感器在4.40×10^(-6)~2.80×10^(-4) mol/L范围内呈良好的线性关系,检测限为1.46×10^(-6) mol/L。用该传感器测定了黑茶中芦丁的含量,获得较好结果。A molecularly imprinted polymer with incorporated graphene（GR）was fabricated as a electrochemical sensor for determination of rutin.The polymer membrane was prepared by electropolymerization with rutin as template molecule and o-aminophenol as functional monomer.The electrochemical behavior of rutin on the modified electrode was studied in detail using differential pulse voltammetry（DPV）and cyclic voltammetry（CV）.Compared with bare gold electrode,the peak current increased clearly on the GR modified gold electrode in [Fe（CN）_6]^（3-/4-） solution.GR could improve the sensitivity of the imprinted polymer sensor for detection of rutin obviously.Under the optimized conditions,a logarithmic linear relationship between peak current and rutin concentration was found at the range of 4.40×10^（-6）-2.80×10^（-4） mol/L with a detection limit of 1.46×10-6 mol/L.It was used for the determination of rutin from black tea with satisfactory results.

关 键 词：分子印迹传感器 循环伏安法 石墨烯 芦丁 

分 类 号：O657.1[理学—分析化学]