64排螺旋CT低剂量对比剂在CT肺动脉血管造影检查中应用的可行性分析  

Feasibility Analysis of Application of 64-slice Spiral CT Low Dose Contrast Medium in CT Pulmonary Angiography

作　　者：姚利华[1] 金彪[2] 卞柳利[1] 王永杰[1] 

机构地区：[1]上海交通大学医学院附属新华医院崇明分院CT室,上海202150 [2]上海交通大学医学院附属新华医院放射科,上海200092

出　　处：《中国CT和MRI杂志》2017年第9期55-57,118,共4页Chinese Journal of CT and MRI

基　　金：国家自然科学基金项目,编号:81160416

摘　　要：目的分析64排螺旋CT低剂量对比剂在CT肺动脉血管造影检查中的应用可行性。方法选取我院2012年11月至2014年11月临床怀疑为肺动脉栓塞的患者64例,随机抽签分为两组,每组32例,低剂量组使用30m L对比剂,常规剂量组使用70m L对比剂。比较两组患者肺血管强化CT值、图像噪声、信噪比、对比噪声比、主观图像质量评分及不良反应发生率,比较两组诊断肺栓塞的灵敏度、漏诊率、特异度和误诊率。结果常规剂量组肺静脉血管强化CT值较低剂量组显著较高(P<0.05);低剂量组不良反应发生率为12.5%较常规剂量组43.75%显著较低(P<0.05)。结论在CT肺动脉血管造影检查中应用64排螺旋CT低剂量对比剂可以满足临床诊断需求,在图像质量以及对肺栓塞诊断的准确度、敏感度和特异度方面与使用常规剂量无显著差异,且患者不良反应发生率降低,值得临床应用推广。Objective To analyze feasibilityof application of 64-slice spiral CT low dose contrast medium in CT pulmonary angiography.Methods 64 patients suspected clinically as pulmonary embolism in our hospital from November 2012 to November 2014 were divided by random lot method into two groups, 32 cases in each group, low dose group used 30mL contrast medium, routine dose group used 70mL contrast medium. Vasa publica enhanced CT value, pattern noise, signal-to-noise ratio, contrast-to- noise ratio, subjective image quality score and incidence of adverse reactions in the two groups were compared, sensitivity, rate of missed diagnosis, specificity and misdiagnosis rate in the diagnosis of pulmonary embolism in the two groups were compared.Results Pulmonary vein vessel enhanced CT value in routine dose group was significantly higher than low dose group（P〈0.05）, incidence of adverse reactions in low dose group was 12.5%, which was significantly lower than routine dose group （43.75%） （P〈0.05）.Conclusion Application of 64-slice spiral CT low dose contrast medium in CT pulmonary angiography can meet the demand of clinical diagnosis, there is no significant difference in inaage quality, accuracy, sensitivity, specificity in the diagnosis of pulmonary embolism compared with routine dose, decreases incidence of adverse reactions of patients, is worth using in clinical practice.

关 键 词：64排螺旋CT 低剂量对比剂 肺动脉血管造影 

分 类 号：R542.54[医药卫生—心血管疾病]