抗凋亡多肽Humanin在心血管疾病中的研究进展  

Research Advances of Humanin in Cardiovascular Disease

作　　者：胡艳清[1,2] 马建群[2,1] 

机构地区：[1]济南大学山东省医学科学院医学与生命科学学院,济南250029 [2]山东省医学科学院附属医院心内科,济南250031

出　　处：《临床心血管病杂志》2017年第8期731-733,共3页Journal of Clinical Cardiology

摘　　要：抗凋亡多肽Humanin(HN)是一种内源性抗细胞凋亡多肽,在多种组织中表达并发挥抗凋亡及其他重要作用。近年来发现其在调控糖脂代谢、动脉粥样硬化、心肌缺血、心肌梗死等方面有关键作用。本文将对HN在心血管方面的研究进展做一综述,以期为心血管疾病的防治提供理论依据。Humanin was an endogenous anti-apoptotic peptide,which was expressed in various tissues and had an anti-apoptotic effect and other protective effects.Recently Humanin was found to play an important role in glucose and lipid metabolism,atherosclerosis,myocardial ischemia reperfusion,myocardial infarction,and so on.This review will focus on studying advances of Humanin in cardiovascular disease,which might enable the development of novel theoretical basis of cardiovascular disease.

关 键 词：抗凋亡多肽 心血管疾病 动脉粥样硬化 糖脂代谢 

分 类 号：R543[医药卫生—心血管疾病]