髂动脉至股深动脉腔内成形术治疗下肢动脉硬化闭塞症效果观察  

Observation on the effect of iliac artery to deep femoral artery angioplasty on patients with lower limb arteriosclerosis obliterans

作　　者：朱蔚东[1] 王超[1] 樊琪[1] 崔玲伟[1] 李腾宇[1] 马定军 

机构地区：[1]北京中医药大学东直门医院东区神经血管外科,101100

出　　处：《中国综合临床》2017年第7期635-638,共4页Clinical Medicine of China

摘　　要：目的 探讨髂动脉至股深动脉腔内成形术对下肢动脉硬化闭塞症（LEASO）患者术后下肢缺血症状的改善及病程恢复的影响.方法 选取我院2013年12月至2016年7月收治的104例LEASO患者,根据不同治疗方案分为观察组和对照组,每组各52例.对照组给予药物保守治疗,观察组行髂动脉至股深动脉腔内成形术治疗.对比两组患者治疗后肢体缺血损伤程度Rutherford分级情况、临床疗效.随访6个月,对比两组患者治疗前及治疗后6个月生存质量评分的差异.结果 （1）Rutherford分级比较：治疗后观察组Rutherford等级分布情况优于对照组,差异有统计学意义（Z=2.160,P=0.031）;（2）临床疗效比较：观察组治疗总有效率94.23%（49/52）高于对照组76.92%（40/52）,差异有统计学意义（χ2=6.310,P=0.012）;（3）生存质量比较：治疗前两组患者生存质量评分比较差异无统计学意义[（55.01±6.32）分与（54.89±6.14）分,t=0.098,P=0.922],治疗后6个月,观察组生存质量评分高于对照组,差异有统计学意义[（69.63±7.51）分与（63.15±6.98）分,t=4.558,P=0.000].结论 髂动脉至股深动脉腔内成形术治疗LEASO,可有效改善患者下肢缺血症状,提高患者的生存质量,疗效显著.Objective To explore the effect of iliac artery to deep femoral artery angioplasty on the improvement of postoperative lower limb ischemic symptoms and recovery in patients with lower limb arteriosclerosis obliterans（LEASO）.Methods One hundred and four LEASO patients in Dongzhimen Hospital of Beijing University of Chinese Medicine from December 2013 to July 2016 were involved in the study and they were divided into control group and observation group according to the treatment program,each group 52 cases.The control group was treated with conservative treatment,and the observation group was treated with iliac artery to deep femoral artery angioplasty.After treatment,the limb ischemic injury degree Rutherford classification and clinical efficacy of the two groups were compared,all patients were followed up for 6 months to compare the survival quality score before and 6-month after treatment.Results （1） Rutherford classification： after treatment,Rutherford classification in the observation group was significantly higher than that of the control group,the result was statistically significant （Z=2.160,P=0.031）;（2） Clinical efficacy： the total effective rate in the observation group （94.23% （49/52）） was higher than that of the control group （76.92% （40/52））,the difference was statistically significant （χ2=6.310,P=0.012）;（3） Life quality： before treatment,there was no significant difference between the two groups in terms of the quality of life score （（55.01±6.32） points vs.（54.89±6.14） points,t=0.098,P=0.922）,but 6 months after treatment,the score of the observation group became higher than that of the control group （（69.63±7.51） points vs.（63.15±6.98） points,t=4.558,P=0.000）.Conclusion The treatment of LEASO using iliac artery to deep femoral artery angioplasty can effectively improve patient＇＇s lower limb ischemic symptoms and life quality.

关 键 词：下肢动脉硬化闭塞症 髂动脉至股深动脉腔内成形术 下肢缺血症状 

分 类 号：R654.4[医药卫生—外科学]