基于数据挖掘的含翼首草藏药组方用药规律研究  

Medication rules for prescriptions containing Pterocephali Herba based on data mining

作　　者：左芳[1] 魏志成[1] 唐策[1] 王文倩[1] 童东 孟宪丽[1] 张艺[1] 

机构地区：[1]成都中医药大学,四川成都611137

出　　处：《中国中药杂志》2017年第16期3213-3218,共6页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81274193)

摘　　要：该研究在收集含翼首草处方的基础上,利用"中医传承辅助平台(V2.0.1)"软件构建数据库,采用关联规则、apriori算法等数据挖掘方法,探讨分析《中国医学百科全书-藏医学》、《藏医成方制剂现代研究与临床应用》、《常用藏成药诠释》等含翼首草组方中翼首草用药规律。分析含翼首草处方中单味药物频次、药物组合频次、关联规则与核心药物组合等。通过处方收集最终纳入方剂215首,共涉及376味药材。通过"频次统计",分析出含翼首草的处方主要治疗感冒发热,瘟毒及各种温热病与关节炎疾病等。高频药物(频次≥15)包括矮紫堇、藏黄连、麻花秦艽等。高频药物组合包括"翼首草、矮紫堇"、"翼首草、藏黄连"、"翼首草、麻花秦艽"等。含翼首草处方主治疾病主要为外感湿热秽毒类病证、发热类、关节炎等疾病,如瘟毒、肺炎以及流行性感冒、类风湿关节炎等,所用药物多具清热解毒、消炎、祛风除湿等功效,亦常与清热类药物配伍运用,用药较为集中,组方法度清晰。This study was aimed to discuss and analyze the medication rules for prescriptions containing Pterocephali Herba in Chinese Medical Encyclopedia-Tibetan Medicine,Tibetan Medicine Prescription Modern Research and Clinical Application,and Interpretation of Common Tibetan Medicines based on the collection of Pterocephali Herba and by using the＂Traditional Chinese Medicine Inheritance Support system（ V2. 0. 1） ＂,with the use of association rules,apriori algorithm and other data mining methods. The frequency of single drug,the frequency of drug combination,the association rule and the combination of core drugs were analyzed. Through collection of the prescriptions,a total of 215 prescriptions were included,involving a total of 376 herbs. Through the＂frequency statistics＂,the prescriptions containing Pterocephali Herba were commonly used to treat cold fever,distemper virus and arthritis. The highest frequently（ frequency≥15） used drugs were Corydalis Herba,Lagotidis Herba,and Gentianae Macrophyllae Radix,et al. The most frequently used drug combinations were ＂Pterocephali Herba,Corydalis Herba＂,＂Pterocephali Herba,Lagotidis Herba＂,and ＂Pterocephali Herba,Gentianae Macrophyllae Radix＂et al. The prescriptions containing Pterocephali Herba were used to primarily treat disease for Tourette syndrome caused by the dampness heat toxin,fever,arthritis etc,such as pestilent toxicity,pneumonia and influenza,rheumatoid arthritis etc. The drugs in the prescriptions mostly had the effects of heat-clearing and detoxifying,anti-inflammatory,dispelling wind and dampness,often in compatible use with heat-clearing drugs. The drug use was concentrated and reflected the clear thought of prescription statutes.

关 键 词：翼首草 用药规律 数据挖掘 关联规则 中医传承辅助平台 

分 类 号：R29[医药卫生—民族医学]