不同民族和地区女性围绝经期高血压中医证型与靶器官损害相关性研究  

ASSOCIATION BETWEEN HYPERTENTION TCM SYNDROME TYPES AND TARGET ORGAN INJURY IN PERIMENOPAUSAL PERIOD OF WOMEN FROM DIFFERENT NATIONALITIES AND REGIONS

作　　者：祖力胡马尔.玉素甫 董晶晶 郭蔚[2] 刘永明[2] 

机构地区：[1]乌鲁木齐市中医医院,新疆乌鲁木齐830000 [2]上海中医药大学附属曙光医院

出　　处：《齐鲁医学杂志》2017年第3期301-304,307,共5页Medical Journal of Qilu

基　　金：国家自然科学基金资助项目(81102671);上海市教育委员会科研创新资助项目(2012JW43);上海市中医临床重点实验室资助项目(14DZ2273200)

摘　　要：目的观察不同民族、地区女性围绝经期高血压病人中医证型分布规律及其与靶器官损害的相关性。方法选取300例不同民族、地区女性围绝经期高血压病人,采集其一般资料、中医症状以及靶器官损害资料。比较维吾尔族(简称维族)和汉族、新疆地区和上海地区汉族女性围绝经期高血压病人中医证型分布、24h动态血压、颈动脉内中膜厚度(IMT)、颈动脉斑块检出率和室间隔厚度。结果维族组围绝经期高血压病人中医证型分布从高到低依次为肝阳上亢、痰湿壅盛、肝肾阴虚和气阴两虚,汉族组病人依次为肝肾阴虚、肝阳上亢、气阴两虚和痰湿壅盛,差异有统计学意义(χ2=12.61,P<0.05)。新疆地区汉族围绝经期高血压病人中医证型分布从高到低依次为肝阳上亢、肝肾阴虚、气阴两虚和痰湿壅盛,上海地区病人中医证型分布从高到低依次为肝肾阴虚、肝阳上亢、气阴两虚和痰湿壅盛,差异无统计学意义(P>0.05)。维族组病人的24h收缩压和24h平均动脉压高于汉族组,差异有统计学意义(t=2.85、3.46,P<0.05);新疆地区汉族组病人24h收缩压、24h舒张压、24h平均动脉压较上海地区汉族组病人高,但差异无统计学意义(P>0.05);各组均以肝阳上亢证病人血压最高。维族组病人颈动脉IMT、颈动脉斑块检出率均高于汉族组病人,差异有统计学意义(t=4.76,χ2=7.35,P<0.05);新疆地区汉族组病人颈动脉IMT、颈动脉斑块检出率均高于上海地区汉族组病人,差异有统计学意义(t=10.90,χ2=5.26,P<0.05)。维族组病人室间隔厚度高于汉族组病人,差异有统计学意义(t=2.52,P<0.05);新疆地区汉族组病人室间隔厚度大于上海地区汉族组病人,差异有统计学意义(t=3.31,P<0.05)。结论维族组女性围绝经期高血压病人中医证型以肝阳上亢最为常见,汉族组病人以肝肾阴虚最为常见。维族组病人血压较汉族组病人高,新疆地区汉族�Objective To investigate the distribution of traditional Chinese medicine（TCM）syndrome types in patients with perimenopausal hypertension from different nationalities and regions,and the association with target organ injury. Methods Three hundred women with perimenopausal hypertension from different nationalities and regions were enrolled,and their general information,TCM symptoms,and target organ injury information were collected.TCM syndrome types,24 hambulatory blood pressure,carotid intima-media thickness（IMT）,detection rate of carotid plaque,and interventricular septal thickness were compared between the women with perimenopausal hypertension of Uygur and Han nationalities and between the Han patients from Xinjiang and Shanghai. Results In the Uygur group,the TCM syndrome types in patients with perimenopausal hypertension,listed from more common to less common,were as follows：upper hyperactivity of liver Yang,phlegm-dampness stagnation,liverkidney Yin deficiency,deficiency of both Qi and Yin.In the Han group,the TCM syndrome types,listed from more common to less common,were as follows：liver-kidney Yin deficiency,upper hyperactivity of liver Yang,deficiency of both Qi and Yin,and phlegm-dampness stagnation.There was a significant difference in the distribution of TCM syndrome types between the two groups（χ2=12.61,P〈0.05）.In the Han patients from Xinjiang,the TCM syndrome types,listed from more common to less common,were as follows：upper hyperactivity of liver Yang,liver-kidney Yin deficiency,deficiency of both Qi and Yin,and phlegm-damp-ness stagnation.In the Han patients from Shanghai,the TCM syndrome types,listed from more common to less common,were as follows：liver-kidney Yin deficiency,upper hyperactivity of liver Yang,deficiency of both Qi and Yin,and phlegm-dampness stagnation.There was no significant difference in the distribution of TCM syndrome types between the two groups（P〉0.05）.The patients inUygur group had significantly higher 24 hsystolic pressure and 24 h mean arte

关 键 词：高血压 围绝经期 地区 民族 医学 中国传统 危及器官 

分 类 号：R544.1[医药卫生—心血管疾病] R259[医药卫生—内科学]