摩拉过敏原检测与治疗在婴幼儿喘息性疾病中的临床应用研究  

The study of the use of Murrah allergy testing and treatment in vilamoura wheezing infants

作　　者：谭杰[1] 覃敏[1] 杨晓祥[1] 苏晓[1] 林映彤 吴丽[1] 余尚扬[1] 胡雪桦[1] 李英乔[1] 韦少玲[1] 秦伟玲[1] 赵赶[1] 

机构地区：[1]广西壮族自治区妇幼保健院儿科,广西南宁530000

出　　处：《临床和实验医学杂志》2017年第18期1818-1821,共4页Journal of Clinical and Experimental Medicine

基　　金：广西医疗卫生适宜技术研究与开发项目(编号:S201405-01)

摘　　要：目的研究摩拉过敏原检测与治疗在婴幼儿喘息性疾病中的临床应用。方法收集2014年6月至2015年6月收治的婴幼儿过敏性喘息100例,参照随机数表法分成对照组与观察组,每组50例,对照组依据病情进行常规药物治疗(无脱敏治疗),观察组在对照组的基础上加用摩拉生物物理治疗仪生物共振检测系统检测和脱敏治疗(即增加脱敏治疗),治疗后分别进行过敏原检测,比较观察组与对照组治疗前后过敏原检测的结果,并比较治疗前后血清嗜酸性粒细胞趋化因子(Eotaxin)及Ig E水平变化,治疗有效率及复发率。结果对照组与观察组治疗前过敏原比较差异无显著性(P>0.05);对照组治疗前后过敏原无变化,差异无显著性(P>0.05);观察组吸入性过敏原治疗后检出率0.60%低于治疗前10.80%,食入性过敏原治疗后检出率0.28%低于治疗前8.57%,其他过敏原治疗后检出率0低于治疗前6.00%,差异具有统计学意义(P<0.05);治疗后,观察组Eotaxin水平低于对照组(69.63±5.61 vs.74.82±5.51)ng/L,Ig E水平低于低于对照组(86.72±5.53 vs.92.80±5.41)U/L,差异有显著性(P<0.05);观察组治疗有效率(96.00%)高于对照组(84.00%),复发率(4.00%)低于对照组(20.00%),差异有显著性(P<0.05)。结论婴幼儿喘息运用摩拉过敏原检测与治疗操作简单、方便,针对性脱敏的治疗效果确切,提高疗效,降低复发率。Objective The study of the use of Murrah allergy testing and treatment in Vilamoura wheezing infants. Methods 100 cases of vilamoura wheezing infants from 2014-June 2015 were treated,by random number table method they were divided into control group and observation group,50 cases in each group. Control group were accepted conventional drug treatment（ no desensitization therapy）,and the observation group based on the treatment method of the control group accepted Murrah biophysical therapy device bioresonance detection system and desensitization therapy（ ie,increased desensitization therapy）. After treatment,the allergy testing outcome was compared and Eotaxin,serum Ig E levels,treatment effectiveness and recurrence rate before and after treatment were compared. Results There was no difference of allergen in the observation group and the control group before treatment（ P〉0. 05）. Allergens in the control group did not change after treatment（ P〉0. 05）. The inhaled allergen detection rate in observation group after treatment（ 0. 60%） was less than that before treatment（ 10. 80）,food allergens detection rate after treatment（ 0. 28%） was less than that before treatment（ 8. 57%）,other allergen detection rate（ 0. 00%） before treatment was lower than that before treatment（ 6. 00%） with statistically significant difference（ P〈0. 05）. After treatment,Eotaxin levels in the observation group was lower than that of the control group [69. 63 ± 5. 60 vs. 74. 82 ± 5. 51] ng/L,Ig E levels was lower than that of the control group [86. 72 ±5. 53 vs. 92. 80 ± 5. 41]U/L,the difference was significant（ P〈0. 05）. The treatment efficiency of the observation group（ 96. 00%） was higher than that of the control group（ 84. 00%）,the recurrence rate（ 4. 00%） was lower than the control group（ 20. 00%） with statistically significant difference（ P〈0. 05）. Conclusion Murrah allergy testing and treatment in wheezing infants is simple,convenient,exact desensitization t

关 键 词：婴幼儿喘息 摩拉过敏原检测与治疗 脱敏疗法 嗜酸性粒细胞 

分 类 号：R725.6[医药卫生—儿科]