中西医结合治疗老年患者全身麻醉术后认知功能障碍的临床效果  

Clinical Effect of Combined Use of Traditional Chinese and Western Medicine in Treatment of Cognitive Dysfunction after General Anesthesia in Elderly Patients

作　　者：刘德民[1] 张琦[1] 胡春欢 巨长桥[1] 

机构地区：[1]牡丹江医学院第二附属医院,黑龙江牡丹江157011

出　　处：《辽宁中医杂志》2017年第8期1695-1697,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：黑龙江省卫生计生委科研课题(2014-202)

摘　　要：目的:研究旨在评估中西医结合治疗老年患者全身麻醉术后认知功能障碍的临床效果。方法:2012年1月—2015年12月,在该院接受全身麻醉的非心脏外科手术后发生轻度认知功能障碍的患者120例,根据治疗方法的不同,将其分为对照组和观察组,每组各60例,对照组的患者接受了常规西医治疗,观察组的患者在常规西医治疗的基础上,采用补肾益气活血化痰方剂治疗,分别于术前、术后7 d以及术后14 d对患者的认知功能进行评价。结果:两组患者在术前和术后7 d的MMSE和MOCA得分差异无统计学意义(P>0.05);第14天的MMSE和MOCA得分差异有统计学意义(P<0.05),观察组的MMSE和MOCA得分明显高于对照组(P<0.05)。结论:中西医结合治疗可以有效地改善全身麻醉后的认知功能障碍,值得在临床大力推广应用。Objective： To evaluate the clinical effect of integrated traditional Chinese and Western medicine in the treatment of cognitive dysfunction after general anesthesia in elderly patients. Methods： From January 2012 to December 2015,120 patients with mild cognitive impairment who underwent general anesthesia after noncardiac surgery were divided into control group and observation group according to different treatment methods,each group 60 cases. The control group＇s patients received conventional Western medicine treatment. The patients in the observation group were treated with Bushen Yiqi Huoxue Huatan Recipe on the basis of conventional western medicine treatment. The cognitive function of the patients was evaluated before operation,7 and 14 days after operation. Results： There was no significant difference in MMSE or MOCA scores between the two groups before and after operation（ P〈0. 05）. There was significant difference in MMSE and MOCA scores between the two groups（ P〈0. 05）. The MMSE and MOCA scores of the observation group were significantly higher than those of the control group（ P〈0. 05）. Conclusion： Combination of traditional Chinese and western medicine can effectively improve the cognitive dysfunction after general anesthesiaand it is worthy to be popularized in clinical practice.

关 键 词：全身麻醉 认知功能障碍 中西医结合治疗 

分 类 号：R614.2[医药卫生—麻醉学]