复发多发性骨髓瘤患者预后因素分析  

Analysis of prognostic factors of patients with multiple myeloma recrudescence

作　　者：屈敏[1] 

机构地区：[1]攀钢集团总医院血液肿瘤科,攀枝花617023

出　　处：《东南国防医药》2017年第4期376-379,共4页Military Medical Journal of Southeast China

摘　　要：目的探讨复发多发性骨髓瘤患者预后的影响因素。方法选取48例复发多发性骨髓瘤患者,在患者入院时收集患者的性别、年龄等临床资料,并在患者治疗后收集患者的实验室、影像学检查结果,计算出患者的生存期。结果血红蛋白、血清白蛋白、骨髓浆细胞、血肌酐、血沉和骨病分级与复发多发性骨髓瘤患者的预后密切相关,差异具有统计学意义(P<0.05)。复发多发性骨髓瘤患者预后的logistic多因素回归分析中,骨髓浆细胞、骨病分级是复发骨髓瘤患者预后的独立因素。结论骨髓浆细胞和骨病分级是影响复发多发性骨髓瘤患者预后的独立因素。Objective To investigate the prognostic factors of patients with multiple myeloma recrudescence. Methods 48 patients with recurrent multiple myeloma were selected in the hospital, and the clinical data of patients were collected after patients were admitted, such as gender, age, et al. After the different treatment, laboratory and imaging examination results were also collect- ed, and the overall survival of patients were calculated. Results Hemoglobin, serum albumin, bone marrow plasma cells, serum ereatinine, ESR and bone disease classification were closely related with the prognosis of patients with recurrence multiple myeloma, and the difference was statistically significant （P〈0.05）. In the logistic multivariate regression analysis of prognostic factors in patients with recurrence multiple myeloma, bone marrow plasma cells and bone disease classification were the independent prognostic factors of patients with recurrence rnuhiple myeloma. Conclusion Bone marrow plasma cells and bone disease classification are the independent prognostic factors of patients with recurrence multiple myeloma.

关 键 词：多发性骨髓瘤 复发 骨髓浆细胞 骨病分级 预后 

分 类 号：R733.3[医药卫生—肿瘤]