补肾活血法对前列腺增生大鼠血浆TXB_2、6-keto-PGF_(1α)、LPO和红细胞SOD的影响  

Effect of the Method of Bushenhuoxue on Plasma TXB_2、6-keto-PGF_(1α) 、LPO and RBC SOD in Rats with BPH

作　　者：何清湖[1] 郑毅春[2] 李翾[2] 

机构地区：[1]湖南中医学院中西医结合系,湖南长沙410007 [2]湖南中医学院,湖南长沙410007

出　　处：《中国中医基础医学杂志》2002年第7期18-19,22,共3页JOURNAL OF BASIC CHINESE MEDICINE

摘　　要：目的 :观察补肾活血法对前列腺增长症大鼠血浆TXB2 、6 keto PGF1α、LPO和红细胞SOD的影响。方法 :用丙酸睾丸素诱发大鼠前列腺增生症模型 ,以补肾活血方前列舒通颗粒剂灌胃。结果 :补肾活血方前列舒通颗粒可调节血浆TXB2 、6 keto PGF1α之间平衡 ,改善LPO和红细胞SOD活力。结论 :补肾活血法治疗BPH的取效可能与其改善前列腺素和自由基的作用有关。To observe the effect of the method of Bushenhuoxue on plasma TXB 2、6 keto PGF 1α 、LPO and RBC SOD in rats with BPH,the rat models with BPH were induced through injecting testosterone propionate,perfused with Qian Lie shu Tong granuler of Bushenhuoxue.The result shows that QianLieShuTong granuler of Bushenhuoxue can adjust the balance between plasma TXB 2 and 6 keto PGF 1α ,improve the vigour of LPO and RBC SOD.It suggest that the effect of the method of bushenhuoxue on BPH might has association with improving the action between prostaglandin and free radical.

关 键 词：TXB2 6-KETO-PGF1Α LPO 补肾活血法 前列腺增生症 血栓素B2 6-酮-前列环素 过氧化脂质 超氧化物歧化酶 动物模型 

分 类 号：R277.5[医药卫生—中医学] R285.