胺碘酮联合缬沙坦对非瓣膜性持续性心房颤动患者窦性心律的维持作用  

作　　者：黄雪林 

机构地区：[1]陕西省汉中市西乡县人民医院急诊科,陕西西乡723500

出　　处：《中国医疗设备》2017年第B04期276-277,共2页China Medical Devices

摘　　要：目的探讨对非瓣膜性持续性。房颤动患者行胺碘酮＋缬沙坦联合治疗的临床效果。方法将2014年3月-2016年3月我院收治的74例非瓣膜性持性心房颤动患者作为研究对象，根据抛硬币法进行分组，正面为对照组，反面为实验组，各37例。对照组行胺碘酮治疗，实验组则行胺碘酮＋缬沙坦联合治疗，观比较两组左心房内径的变化情况以及心律维持率。结果实验组左心房内经显著小于对照组，实验组心律维持率32例（86．49％）显著高于对照组22例（59.46％），且对照均存在P〈0．05，有统计学上的意义。结论对非瓣膜性持续性。房颤动患者行胺碘酮＋缬沙坦联合治疗，能够在一定程度上提高患者心律维持率抑制左心房内径的增大。Objective To evaluate the clinical efficacy of amiodarone plus valsartan in the treatment of nonvalvular persistent atrial fibrillation. Methods： From March 2014 March 2016, 74 non-- valvular persistent atrial fibrillation patients were randomly divided into two groups according to the coin-- dropping method the positive group was t control group the negative group was the experimental group. The control group was treated with amiodarone, and the experimental group was treated with amiodarone w sartan. The changes of left atrium diameter and heart rate were observed and compared between the two groups. Results In the experimental group, the left atrium was signi candy smaller than the control group. The rhythm preservation rate of the experimental group was significantly higher than that of the control group （86.49 % vs. 59.46 % , P 0.05 ）. Conclusion： Amiodarone plus valsartan combined with amiodarone and valsartan in patients with nonvalvular persistent atrial fibrillation can improve cardiac rhythm mai tenance and increase the diameter of left atrium in a certain extent.

关 键 词：胺碘酮 缬沙坦 非瓣膜性持续性心房颤动患者 窦性心律 维持作用 

分 类 号：R453[医药卫生—治疗学]