归脾汤加减对老年高血压病患者血压、负性情绪及生活质量的影响  

The Effect of modified Guipi Decoction on Blood Pressure,Negative Emotion and Life Quality of Elderly Hypertension Patient

作　　者：崔维[1] 王龙安[1] 

机构地区：[1]河南中医药大学第三附属医院,河南郑州450008

出　　处：《中医学报》2017年第8期1503-1506,共4页Acta Chinese Medicine

基　　金：河南省科技攻关项目(102102310108)

摘　　要：目的:观察归脾汤加减对老年高血压病患者血压、负性情绪和生活质量的影响。方法:将104例患者随机分成对照组和试验组,对照组50例和试验组54例。对照组采用钙通道阻滞剂治疗,必要时给予联用利尿剂和(或)血管紧张素转换酶抑制剂治疗。试验组在对照组治疗基础上加用归脾汤治疗。分别于治疗前后测量两组患者血压,抑郁自评量表(Self-rating depression scale,SDS)和焦虑自评量表(Self-Rating Anxiety Scale,SAS)评估患者负性情绪,健康状况问卷(Short Form 36 Health survey Questionnaire,SF-36)评估患者生活质量并进行比较分析。结果:试验组治疗前血压为(167.7±18.3)/(99.7±6.9)mm Hg(1 mm Hg=0.133 k Pa),SAS评分为(48.5±5.7)分,SDS评分为(49.6±6.5)分;治疗8周后血压为(148.7±15.4)/(92.3±6.5)mm Hg,SAS评分为(34.2±5.2)分,SDS评分为(37.4±6.7)分。而对照组治疗前血压为(168.2±17.4)/(99.4±6.7)mm Hg,SAS评分为(48.3±6.2)分,SDS评分为(48.9±5.8)分;治疗8周后血压为(155.7±16.5)/(94.3±5.7)mm Hg,SAS评分为(39.6±5.7)分,SDS评分为(44.1±5.6)分。两组治疗前血压、SAS和SDS评分比较,无统计学差异(P>0.05),治疗后上述指标均显著下降,差异有统计学意义(P<0.05)。试验组治疗后SF-36各因子及总体健康评分均优于对照组,差异均有统计学意义(P<0.05)。结论:对老年高血压病患者采用归脾汤加减辅助治疗,有助于改善患者血压水平及负性情绪,并提高生活质量。Objective：To investigate the clinical effect of modified Guipi decoction on blood pressure, negative emotion and life quality of elderly hypertension patients. Methods ： 104 patients were randomly divided into the control group of 50 cases and the ex- perimental group of 54 cases. The control group was given calcium channel blocker, and treated with diuretics and/or angiotensin- converting enzyme inhibitors when necessary. The experimental group was treated with Guipi decoction based on the control group. Measuring the blood pressure of the two groups before and after treatment respectively, Self-rating depression scale（SDS） and Self- Rating Anxiety Scale （SAS） were used to assess the negative emotions of patients, Short Form 36 Health survey Questionnaire （SF- 36） was used to evaluate the life quality of the patients and a comparative analysis. Results：The blood pressure of the experimental group was （ 167.7 ± 18.3） / （99.7 ± 6.9 ） mmHg, the SAS score was （48.5 ± 5.7 ） points, and the SDS score was （49.6 ±6. 5） points before treatment;and the blood pressure was （148.7 ± 15.4）/（92.3 ± 6.5 ） mmHg, the SAS score was （34.2 _± 5.2 ） points, and the SDS score was （37.4 _± 6.7 ） points after 8 weeks. While the blood pressure was （ 168.2 ±17.4） / （99.4 ±6.7） mmHg,SAS score was （48.3 ±.2） points,SDS score was （48.9 ±0.8） points of control group before treatment;and the blood pressure was （155.7 ±16.5） / （94.3 ± 5.7） mmHg, the SAS score was （39.6 ±5.7 ） points, and the SDS score was （ 44. 1 ±5.6 ） points after 8 weeks of treatment. There was no significant difference in blood pressure, SAS and SDS score between the two groups （ P 〉 0.05 ） , the above indexes were significantly decreased after treatment, but the decline of the control group was lower than that of the experimental group （ P 〈 0.05 ）. The SF-36 factor and the overall health score of the experimental group were better than those of the control group a

关 键 词：老年高血压病 血压 抑郁 焦虑 生活质量 中医药治疗 中西医结合 

分 类 号：R259.441[医药卫生—中西医结合]