稳定型心绞痛应用曲美他嗪和倍他乐克联合治疗的效果评估  

Evaluation efficacy of combination therapy with trimetazidine and metoprolol in stable angina pectoris

作　　者：闫明[1] 李莹[1] 魏晓冬[1] 芦珊[1] 

机构地区：[1]哈尔滨市第一医院心血管内科,哈尔滨150001

出　　处：《黑龙江科学》2017年第14期16-17,共2页Heilongjiang Science

摘　　要：采用回顾性分析法选择2014年10月—2016年9月期间我院收诊的90例稳定型心绞痛患者,随机分观察组与对照组各45例,观察组患者均行曲美他嗪20 mg 3次/d与倍他乐克25 mg 2次/d药物治疗方法;对照组患者实施倍他乐克25 mg 2次/d、伯基与长效型硝酸脂类治疗方法,10周设置为1个疗程。对两组患者治疗前后心绞痛发作状况、运动耐受优化状况、心电图变化状况进行观察分析。1个疗程后,观察组与对照组患者心绞痛发作次数均有不同程度降低,血压、心率、运动耐受与心电图都有所变化,治疗后观察组患者变化程度显著优于对照组,差异有统计学意义(P<0.05)。曲美他嗪与倍他乐克联合治疗稳定型心绞痛能使患者临床症状显著改善,毒副作用较低,安全性较高,具有推广与应用价值。Retrospective analysis was used to select 90 patients with stable angina pectoris from October 2014 to September 2016,n=45.The observation group were treated with trimetazidine 20 mg 3 times/d with metoprolol 25mg 2 times/d;the control group with metoprolol 25 mg 2 times/d,primary and long-acting nitric acid lipid treatment,10 weeks set to 1 course of treatment.After 1 course of treatment,the number of angina pectoris was decreased in observation group and control group.The changes of blood pressure,heart rate,exercise tolerance and electrocardiogram were observed.After treatment,the degree of change was significantly better than that of the control group（P0.05）.The combination of trimetazidine and metoprolol in the treatment of stable angina can improve the clinical symptoms,which has popularization and application value.

关 键 词：稳定型心绞痛 曲美他嗪 倍他乐克 联合治疗 

分 类 号：R541.4[医药卫生—心血管疾病]