蒙脱土负载试剂催化下的四组分“一锅煮”反应  

One-pot Synthesis Reaction Through Four-component Condensation Using Montmorillonite Supported Reagent Catalyst

作　　者：李风起[1] 

机构地区：[1]青岛科技大学化学与分子工程学院,山东青岛266042

出　　处：《皮革与化工》2017年第4期35-37,共3页Leather And Chemicals

摘　　要：本文以酸处理蒙脱土K10为载体,分别将三氯化铁(FeCl_3)和硝酸铈铵(CAN)负载在蒙脱土上制成负载型催化剂,用于苯偶姻、苯甲醛、苯胺和醋酸铵四组分一锅煮合成1,2,4,5-四苯基咪唑。并通过熔点测定、红外光谱、核磁共振、元素分析等对产物的结构进行了表征。实验表明以蒙脱土K10固载CAN为催化剂,由苯偶姻、苯胺、醋酸铵和苯甲醛四组份一锅煮合成四取代咪唑。具有反应时间短、收率高、操作简便、催化剂活性高、选择性好等优点。In this paper, by using acid-treated montmorillonite K10 as catalyst supporters,montmorillonite-supported FeCl_3 and CAN catalysts were prepared. The 1,2,4,5-four phenyl imidazole was obtained via a four-components reaction of benzoin, benzaldehyde, phenyl amine and ammonium acetate by Montmorillonite supported reagent catalyst. Its structure was characterized by melting point determination, IR, NMR spectroscopy and elemental analysis. Experiment result showed that CAN/Montmorillonite K10 was an efficient for one-pot synthesis of tetrasubstituted imidazole. The reaction had the advantages of short reaction time, excellent yield, easy work-up, high activity and selectivity.

关 键 词：蒙脱土K10 三氯化铁 硝酸铈铵 负载试剂 催化剂 

分 类 号：O643.36[理学—物理化学]