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机构地区:[1]武汉大学人民医院重症医学科,武汉430060
出 处:《医学综述》2017年第17期3432-3436,3440,共6页Medical Recapitulate
摘 要:近年来,关于阴茎勃起功能障碍(ED)的研究取得了长足进步。这得益于基因学在阴茎血管的平滑肌舒张与收缩方面的研究,同时ED的分子学及临床学研究亦在不断加深,尤其是对ED的病理机制、分类及相关诊断和治疗的认识也较前有了极大提高。阴茎ED分为器质性和心因性,其中器质性ED的病理生理机制及类别复杂,且诊断和治疗方式多样,如口服5型磷酸二酯酶抑制剂、海绵体注射、阴茎假体植入、介入治疗、干细胞治疗等。未来,基因分子学及临床学的研究将为ED的诊断和治疗提供新思路。In recent years, the research on penile erectile dysfunction (ED) has made great progress. Thanks to the study of genetics in smooth muscle relaxation and contraction, and the molecular and clinical study on ED have also made a great progress, especially the understanding of the pathogenesis, classification and related treatment. ED can be divided into organic and psychogenic, and the mechanisms and categories of organic ED are complex. The diagnosis and treatment methods are diverse, such as phosphodiesterase type 5 inhibitors, intracavernous injection, penile prosthesis, interventional therapy, stem cell therapy etc. In future, studies on clinical and medical genetics level will provide new ideas for the diagnosis and treatment of ED.
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