抗-C伴随自身类抗-e的鉴定  

Identification of anti-C alloantibodies accompanying anti-e autoantibodies

作　　者：皮兰敢[1] 何章勇[1] 

机构地区：[1]郴州市第一人民医院检验医学中心,湖南郴州423000

出　　处：《中国输血杂志》2017年第7期693-695,共3页Chinese Journal of Blood Transfusion

摘　　要：目的分析在院患者住院期间产生的抗体特性。方法通过进行红细胞抗体筛选、鉴定,检测不同时间段抗体变化,高速毛细管离心法分离患者红细胞测定Rh表型等多种方法对抗体特性进行多方面的探究。结果抗体产生初期检出同种抗-C和非特异性自身抗体,然后自身抗体成熟为有特异性的抗-e。在住院时间段内抗-C效价均较低(<4)。结论抗体的鉴定尽可能在方法学上从各个方面进行综合分析,以便找到真正相合的血液。Objective To confirm the specificity of antibodies recently found in a hospitalized patient. Methods Meth- ods including antibody screening, antibodies identification, alloantibody titers, isolation of red blood cells by high speed capillary centrifugation and determination of Rh phenotype were employed to investigate the characteristics of antibodies. Results Anti-C alloantibody and anti-e autoantibodies were detected in the patient. Autoantibodies were non-specific in the early stages, and gradually changed into specific auti-e antibodies. The titers of anti-C alloantibody were always lower than 4.Conclusion The identification of antibodies should be integrated as far as possible in various aspects of methodology .

关 键 词：抗-C同种抗体 抗-e特异性自身抗体 类同种抗体 

分 类 号：R457.11[医药卫生—治疗学]