多模态磁共振成像在乳腺癌诊断中的应用价值  

Application value of multi-modality magnetic resonance imaging in diagnosis of breast cancer

作　　者：吴津民[1] 王海宝[1] 徐丽艳[1] 李仁民[1] 刘灿[1] 马宁[1] 鲁学婷 

机构地区：[1]安徽医科大学第一附属医院放射科,合肥230022

出　　处：《安徽医学》2017年第8期963-965,共3页Anhui Medical Journal

基　　金：国家自然科学基金(项目编号:81171326)

摘　　要：目的应用多模态MRI包括弥散加权成像和动态增强扫描(DCE-MRI)对乳腺癌患者的检测,分析其MRI相关影像特征,探讨其对该病诊断的准确性。方法回顾分析2012年1月至2016年8月于安徽医科大学第一附属医院术前行MRI检查和术后病理或穿刺活检证实的16例乳腺癌女性患者多模态MRI数据资料,统计分析表观弥散系数(ADC)、相对表观弥散系数(r ADC)值及动态时间信号强度曲线图像(TIC)。结果 16例患者MRI显示病灶多见分叶(75.00%)、毛刺(75.00%),边界不清(81.25%)。ADC值为(0.92±0.19)×10^(-3)mm^2/s,r ADC为(0.56±0.13)×10^(-3)mm^2/s。TIC:Ⅱ型4例(25.00%),Ⅲ型12例(75.00%),无符合Ⅰ型的病例。结论多模态MRI用于乳腺癌的检查,结合病变形态学改变、DCE-MRI的TIC曲线形态和ADC值,可以提高乳腺癌的诊断正确率。Objective To further improve the diagnostic accuracy of breast cancer by application of multi - modality MRI, including diffusion - weighted imaging （DWI） and dynamic contrast - enhanced （DCE） scanning, in the detection of patients with breast cancer and the analysis of characteristics of the MRI images. Methods The multi - modality MRI data of 16 female patients with breast cancer, diag-nosed by preoperative MRI and postoperative pathological examination or biopsy in our hospital from Jan 2012 to Aug 2016, were retrospec-tively analyzed. Values of apparent diffusion coefficient （ADC） and relative apparent diffusion coefficient （ rADC） were calculated, and dy-namic time - signal intensity curve （TIC） was constructed. Results In the MRI images of 16 patients, lesions often tended to be lobulated, spiculated （75. 0% ） and ill - defined. Their ADC and rADC values were （0. 92 ±0. 19） × 10 3 mm2 A and （0. 56 ±0. 13） ×10 3 mm2 A , respectively. As for TIC, 4 cases of type II （25. 0 % ） and 12 cases of type III （75. 0 % ） were found, with no case of type I. Conclusion When applied in detection of breast cancer, multi - modality MRI, combining with morphological change of lesions, TIC curve of DCE - MRI and ADC value, may improve the diagnostic accuracy of breast cancer.

关 键 词：乳腺癌 弥散加权成像 动态增强磁共振 多模态磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]