急性心肌梗死患者血清白细胞介素2和白细胞介素6水平的临床研究  

Clinical study on serum levels of interleukin-2 and interleukin-6 in patientswith acute myocardial infarction

作　　者：赵晖[1] 苏毅[1] 马欣[1] 

机构地区：[1]河南省焦作市第二人民医院心内一区,焦作454000

出　　处：《右江医学》2017年第4期465-467,共3页Chinese Youjiang Medical Journal

摘　　要：目的通过检测急性心肌梗死(AMI)患者血清白细胞介素2(IL-2)和白细胞介素6(IL-6)的水平,探讨IL-2和IL-6在急性心肌梗死中的发病机制和作用。方法实验分为对照组(NC组)与急性心肌梗死组(AMI组),检测两组患者血清IL-2和IL-6水平。结果 AMI组IL-2和IL-6明显高于NC组,差异有统计学意义(P<0.05)。在AMI组中IL-2和IL-6之间呈正相关(r=0.733,P<0.05),在NC组中IL-2和IL-6之间无统计学关联(P>0.05)。结论IL-2和IL-6可能参与了急性心肌梗死的炎性反应,炎性反应有可能是急性心肌梗死的发病机制之一。Objective To investigate the pathogenesis and role of IL-2（interleukin-2） and IL-6（interleukin-6） in acute myocardial iniarction（ AMI） by detecting serum IL-2 and IL-6 levels in patients with AMI.Methods The objects were divid-ed into control group （NC group） and acute myocardial infarction group （AMI group ） ,and the serum IL-2 and IL-6 levels of the tw-o groups were detected.Results Serum levels of IL-2 and IL-6 in the AMI group were significantly higher than those of the control group （P〈0.05）.The AMI group showed a very high positive correlation between IL-2 and IL-6 （ r = 0.733）.But there was no correlation between IL-2 and IL-6 in the NC group（ P〉0.05）.Conclusion IL-2 and IL-6 may involve in the oc-currence and development of inflammatory reaction in AMI, and inflammatory response may be one of the pathogenesis of AMI.

关 键 词：急性心肌梗死 血清IL-2 血清IL-6 

分 类 号：R542.22[医药卫生—心血管疾病]