腹针疗法结合康复训练治疗脑卒中后疲劳的临床效果及对炎症因子的影响  

Effect and Inflammatory Mechanism of Abdominal Acupuncture Combined with Rehabilitation Training for Patients with Post-Stroke Fatigue

作　　者：詹乐昌[1] 潘锐焕[1] 何铭锋[1] 董葱 王秋月[2] 黄珍[3] 詹杰[2] 陈红霞[1] 

机构地区：[1]广东省中医院/广州中医药大学第二附属医院,广州510006 [2]广州中医药大学第二临床医院 [3]广东省佛山市中医院

出　　处：《中西医结合心脑血管病杂志》2017年第16期1966-1968,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广东省中医药管理局项目(No.20151249)

摘　　要：目的观察腹针疗法结合康复训练治疗脑卒中后疲劳(PoSF)的临床疗效及对炎症因子的影响。方法将70例PoSF病人随机分为治疗组与对照组,每组35例。对照组给予基础治疗和常规康复训练,治疗组在对照组治疗的基础上加用腹针治疗,每天1次,每周5次,连续治疗2周。观察两组治疗前后疲劳严重度量表(FSS)、多维疲劳问卷(MFI-20)评分的变化,并检测血清白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)浓度变化。结果治疗前,两组在FSS、MFI-20评分及血清IL-1β、TNF-α、IL-6比较差异无统计学意义(P>0.05);治疗2周后,两组FSS评分、MFI-20评分及血清IL-1β、TNF-α、IL-6低于治疗前,差异有统计学意义(P<0.05),且治疗组下降幅度大于对照组,差异有统计学意义(P<0.05)。结论腹针疗法结合康复训练可改善病人的疲劳程度,其作用机制可能与腹针疗法结合康复训练降低血清致炎因子的浓度有关。Objective To observe the effect of abdominal acupuncture combined with rehabilitation training in patients after stroke with fatigue and explore its possible mechanism.Methods Seventy patients with post-stroke fatigue（PoSF）were randomly divided into the treatment and control groups according to random numbers generated by PEMS3.0.While the patients in the control group were given the basic treatments and conventional rehabilitation training,the patients in the treatment group were additionally given abdominal acupuncture.All patients were treated once a day for two weeks.The fatigue severity scale（FSS）and Multidimensional Fatigue Questionnaire（MFI-20）were conducted before and after the treatments.The contents of serum IL-1β,TNF-α,and IL-6 in patients were also detected at baseline and after treatments.Results At baseline,there were no significant difference between two groups in the scores of FSS and MFI-20,and the contents of serum IL-1β,TNF-α,and IL-6（P〈0.05）.After 2-weeks treaments,there were significant difference between both groups in the scores of FSS and MFI-20,and the contents of serum IL-1β,TNF-α,and IL-6（P〈0.05）.Conclusion Abdominal acupuncture combined with rehabilitation training can alleviate the fatigue in patients with PoSF,and the potential mechanism may be that abdominal acupuncture combined with rehabilitation training can reduce the concentration of serum proinflammatory cytokines.

关 键 词：卒中后疲劳 腹针疗法 康复训练 白细胞介素-1Β 肿瘤坏死因子-Α 白细胞介素-6 中风 

分 类 号：R246.6[医药卫生—针灸推拿学]