辽宁省阜新市农村地区≥60岁老年人群不同年龄段血压控制最适值  

Optimal blood pressure levels in population of ≥60 years age groups: a study in rural areas of Liaoning Fuxin

作　　者：余碧韬 郑黎强[2] 赵苗苗[1] 邹莉玲[1] 孙英贤[3] 李觉[1] 

机构地区：[1]同济大学医学院心肺血管中心,上海200092 [2]中国医科大学附属盛京医院临床流行病科,辽宁沈阳110004 [3]中国医科大学附属第一医院心脏病科,辽宁沈阳110001

出　　处：《同济大学学报（医学版）》2017年第4期102-108,共7页Journal of Tongji University(Medical Science)

基　　金：国家重点基础研究发展计划(2013CB531100)

摘　　要：目的研究辽宁阜新农村地区≥60岁老年人群不同年龄段血压与不良结局发生的相关性,探讨不同年龄段血压控制最适值。方法将纳入人群按60~69岁、≥70岁两个年龄段进行分层,采用Cox比例风险回归模型,在调整其他混杂危险因素后,探究不同年龄段血压与不良结局之间的关系。结果 60~69岁年龄段,相比参照组(收缩压120~129 mm Hg),收缩压<120 mm Hg或者≥140 mm Hg时,不良结局发生的风险性更高;≥70岁年龄段,相比参照组(收缩压130~139 mm Hg),收缩压<120 mm Hg或者≥150 mm Hg时,不良结局发生的风险性更高。60~69岁年龄段,相比参照组(舒张压80~89 mm Hg),舒张压<80 mm Hg或者≥90 mm Hg时,不良结局发生的风险险性更高;≥70岁年龄段,相比参照组(舒张压80~89 mm Hg),舒张压<80 mm Hg或者≥90 mm Hg时,不良结局发生的风险性更高。结论对于辽宁阜新农村地区≥60岁老年人群,60~69岁年龄段收缩压控制在120~139 mm Hg,舒张压控制在80~89 mm Hg,不良结局发生的风险性更低;≥70岁年龄段收缩压控制在120~149 mm Hg,舒张压控制在80~89 mm Hg,不良结局发生的风险性更低。Objective To explore the optimal blood pressure （BP） among different age groups in population aged ^60 years. Methods Total 8 516 residents aged ≥60 years were selected from Fuxin rural area, including 4 897 aged 60 -69 and 3 619 aged ≥70. After adjusting confounding factors, the relationships between BP and adverse outcomes were analyzed by Cox proportional hazards regression model. Results Compared with reference set of systolic blood pressure （SBP of 20-129 mmHg）,subjects aged 60 to 69 years with SBP 〈 120 mmHg or SBP ≥140 mmHg had a higher risk for adverse outcomes; subjects aged ≥70 years with SBP 〈 120 mmHg or SBP≥150 mmHg had a higher risk for adverse outcomes compared with reference set （SBP o f 130 - 139 mmHg）. For diastolic blood pressure （DBP） , subjects both in 60 ？69 age group and ≥70 age group with DBP 〈80 mmHg or DBP ≥ 90 mmHg had a higher risk for adverse outcomes compared with reference set （DBP o f 80 -90 mmHg）. Conclusion The study from Fuxin rural area indicates that i f SBP could be controlled within 120-139 mmHg, DBP could be controlled within 80 -89 mmHg, people in age group 60 -69 years would have a lower risk of adverse cardiovascular outcom es; while for those in age group ≥70 years the SBP and DBP should be controlled to 120 -149 mmHg and 80 - 89 mmHg, respectively.

关 键 词：血压 老年人群 不良结局 COX比例风险回归模型 

分 类 号：R54[医药卫生—心血管疾病]