^(18)F-FDG PET标准脑葡萄糖代谢数据库的建立  

Establishment of standard brain ^(18)F-FDG PET database in Chinese population

作　　者：郭坤[1] 李云波[1] 黄勇[1] 魏熠鑫 张微[1] 袁梦晖[1] 魏龙晓[1] 

机构地区：[1]第四军医大学唐都医院核医学科,西安710038

出　　处：《临床神经外科杂志》2017年第4期263-266,共4页Journal of Clinical Neurosurgery

基　　金：基金项目:2015年度唐都医院新技术新业务

摘　　要：目的运用MIMneuro软件构建反映不同年龄、性别差异的正常中国人脑葡萄糖代谢标准数据库。方法采集78例健康志愿者的脑PET图像,年龄每隔10岁一组,分为8组,男女性别比例相当。用MIMneuro软件进行图像的归一化处理,并根据软件内单脑MRI以及概率MRI进行脑区划分,构建基于区域及体素分析的脑功能数据库。结果建立正常国人脑葡萄糖代谢标准数据库,为临床诊断功能性脑病提供平台,尤其是癫痫患者术前准确定位。结论不同年龄段、不同性别的正常人脑葡萄糖代谢标准数据库为功能性脑疾病的PET诊断提供客观依据,MIMneuro软件的自动定量分析增加临床医生的诊断信心。Objective To establish the standard cerebral glucose metabolism database in different ages and gender in Chinese population by using ^（18）F-FDG PET and MIMneuro software.Methods ^（18）F-FDG PET brain imaging data acquired from 78 healthy volunteers were grouped by age of 10-year interval and divided into 8 groups,gender radio were equal. Brain Align,the landmarkbased deformation algorithm,ensures consistency and accuracy for each case. Regional-based or voxel-based analysis for more confident image interpretation. Results The normal standard ^（18）F-FDG PET database of Chinese population was established,providing quantitative platform for the diagnosis of functional brain disorders,especially accurate preoperative location of epilepsy patients.Conclusions The normal standard ^（18）F-FDG PET database providing objective basis for the interpretation of PET images,the automatic quantitative analysis increases the confidence of clinicians.

关 键 词：18F-FDG PET 数据库 定量分析 

分 类 号：R817.4[医药卫生—影像医学与核医学]