妊娠早期亚临床甲状腺功能减退对妊娠结局的影响  

Influence of Subclinical Hypothyroidism on Pregnancy Outcome in Early Pregnancy

作　　者：沈艳[1] 杨悦[1] 陈刚[1] 刘清秀 

机构地区：[1]民航总医院产科,北京100123 [2]重庆市开州区人民医院产科,重庆405400

出　　处：《中国医药导刊》2017年第7期677-678,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨妊娠早期亚临床甲状腺功能减退(SCH)对妊娠结局的影响。方法:选取笔者所在医院2015年2~11月建档产检并分娩的孕妇588例为研究对象,其中妊娠期间甲状腺功能正常的孕妇作为对照组,共510例,患有SCH的孕妇作为观察组,共78例。比较两组孕妇妊娠结局情况。结果:观察组早产率为14.10%、先兆性流产及流产发生率为15.38%、子痫前期发生率为16.67%、妊娠期糖尿病发生率为25.64%,均显著高于对照组的1.37%、1.18%、2.35%、11.76%,比较差异均有统计学意义(P<0.05)。结论:SCH对孕妇及胎儿会产生不良的影响,早期临床上应及时诊断和采取相应治疗措施,改善妊娠结局。Objective： To investigate the effect of subclinical hypothyroidism（ SCH） on pregnancy outcome in early pregnancy. Methods： 588 pregnant women filing production inspection and delivery in our hospital from Feb 2015 to Nov 2015 were selected as the research object,among whom 510 with normal thyroid function during pregnancy were selected as the control group. And the pregnant women with SCH were selected as the observation group,with a total of 78 cases. Then the pregnancy outcomes of the two groups were compared. Results： Among the patients of observation group,14. 10% premature birth,15. 38% threatened abortion and abortion,16. 67% preeclampsia incidence,25. 64% gestational diabetes incidence was significantly higher than 1. 37%,1. 18%,2. 35% and 11. 76% of the control group,and the differences were significant statistically（ P 0. 05）. Conclusion： SCH has adverse effects on pregnant women and fetuses,and early diagnosis and timely treatment should be taken to improve the outcome of pregnancy.

关 键 词：妊娠早期 亚临床甲状腺功能减退 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]