探讨硬膜外术后罗哌卡因、氢吗啡酮的镇痛效果  

Investigation of Analgesic Effects of Ropivacaine and Hydromorphine for Postoperative Epidural

作　　者：任元华 张莉[1] 赵永军[1] 

机构地区：[1]四川省广元市第一人民医院麻醉科,广元628017

出　　处：《中国医药导刊》2017年第7期725-725,727,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:对罗哌卡因复合氢吗啡酮用于硬膜外术后镇痛的临床效果进行评估。方法:采用随机数字表法将87例择期硬膜外麻醉下手术患者分为罗哌卡因组(罗哌卡因复合氢吗啡酮)44例和左旋布比卡因组(左旋布比卡因复合氢吗啡酮)43例,对比分析两组患者术后不同时间的视觉模拟疼痛评分(VAS)、下肢运动阻滞程度评分、躁动评分(Ramsay)及不良反应的发生情况。结果:两组患者术后24 h VAS评分较术后2 h均显著降低,差异均有统计学意义(P<0.05)。结论:罗哌卡因复合氢吗啡酮用于硬膜外术后镇痛与左旋布比卡因复合氢吗啡酮具有均具有较好的镇痛效果和安全性。Objective： To investigate the clinical analgesic effect of Rostoperative and Hydromorphine for postoperative epidural.Methods： Randomly 87 patients undergoing elective surgery under epidural anesthesia were divided into ropivacaine group（ ropivacaine hydromorphone） 44 cases and levobupivacaine group（ combined levobupivacaine hydromorphone） 43 cases,comparative analysis of visual analogue pain score at different time after operation in the two groups（ VAS）,lower extremity motor block scores and agitation score（ Ramsay） and adverse reactions. Results： The two groups of patients after 24 h VAS scores at 2 h after operation were significantly reduced（ P 0. 05）. Conclusion： Hydromorphone with ropivacaine for postoperative epidural analgesia with levobupivacaine combined with hydromorphone have analgesic effect and good safety.

关 键 词：罗哌卡因 氢吗啡酮 硬膜外术后镇痛 左旋布比卡因 临床效果 

分 类 号：R614[医药卫生—麻醉学]