益生菌治疗变应性鼻炎的研究进展  

The advances of probiotics treatment of allergic rhinitis

作　　者：许洋[1] 赵宇[1] 任健君 王晶[1] 雷蕾[1] 郑永波[1] 

机构地区：[1]四川大学华西医院耳鼻咽喉头颈外科,成都610041

出　　处：《临床耳鼻咽喉头颈外科杂志》2017年第17期1322-1327,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金面上项目(No:81170898);四川省科技计划项目(No:2016HH0064)

摘　　要：1变应性鼻炎的流行病学与发病机制随着城市化进程和空气污染的加重,我国变应性鼻炎（allergic rhinitis,AR）的患病率明显增高。2011年Wang等（[1]）调查我国18座主要城市AR标准化患病率为17.6%,而在2005年的调查中只有4座城市的AR标准化患病率超过15%。AR是鼻部接触变应原后产生的由IgE介导的炎症性疾病（[2]）。AR不仅影响患者的生活质量.Summary In recent years, the prevalence of allergic rhinitis faces an explosion. People＇s understanding about the pathogenesis of this disease goes profound. Probiotics is competent to regulate the balance of immune system, and also can reduce susceptibility towards allergens. Now it is right a hot topic that applying probiotics to remedy allergic rhinitis. Since the data of many researches in this field is at hand, further discuss is needed from experi- mental methods to molecular mechanisms.

关 键 词：益生菌 鼻炎 变应性 调节性T细胞 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]