临床药师参与1例扁桃体癌患者化疗方案的制订和药学监护  

Formulation of Chemotherapy Program and Pharmaceutical Care for a Patient with Tonsil Cancer by Clinical Pharmacists

作　　者：金秉巾[1] 

机构地区：[1]青海省人民医院药学部,西宁810007

出　　处：《中国药房》2017年第26期3723-3725,共3页China Pharmacy

摘　　要：目的:探讨临床药师在扁桃体癌患者药物治疗中的作用。方法:临床药师参与1例扁桃体癌患者的药物治疗过程,参考相关指南、文献以及化疗药物作用特点,结合患者的临床症状和经济状况,从有效性、安全性出发协助医师制订奈达铂联合多西他赛的化疗方案(注射用奈达铂100 mg,d1;50 mg,d2,ivgtt,qd+多西他赛注射液100 mg,d1,ivgtt,qd,每3周为1个周期);并密切监测有无化疗致骨髓抑制、胃肠道反应、过敏反应等不良反应发生,并行化疗预处理药物的使用,化疗期间饮食、饮水,不良反应预防等用药教育及出院教育。结果:医师采纳临床药师建议,患者顺利完成本周期化疗,且未出现相关不良反应。结论:在扁桃体癌化疗方案尚无统一标准的情况下,临床药师结合患者的临床特征、药物作用特点、经济状况,协助医师制订化疗方案,并积极开展药学监护,保证了患者化疗的安全性和有效性。OBJECTIVE： To explore the role of clinical pharmacists in the drug therapy for patient with tonsil cancer. METH- ODS： Clinical pharmacists participated in the drug therapy for a patient with tonsil cancer. Referring to related clinical guidelines, literatures and the characteristics of chemotherapy drug effects, combined with clinical symptoms and economic situation of pa- tient, clinical pharmacists assisted physicians to formulate chemotherapy plan of nedaplatin combined with docetaxel （Nedaplatin for injection 100 mg, dl; 50 mg,d2; ivgtt, qd＋Docetaxel injection 100 rag, dl, ivgtt, qd, every 3 weeks for 1 cycle）according to effectiveness and safety. Clinical pharmacists closely monitored the occurrence of ADR as depression of bone marrow, gastroin- testinal reaction and allergic reaction, and provided medication education and discharge education, such as the use of pretreated che- motherapy drugs, diet and drinking water during chemotherapy, the prevention of ADR, etc. RESULTS： Physicians adopted the suggestions of clinical pharmacists. The patient completed chemotherapy smoothly, and no ADR was found. CONCLUSIONS： In the case of there is no unified standard for chemotherapy program of tonsil cancer at present, clinical pharmacists assist physicians to formulate chemotherapy plan according to the patient＇s condition, the characteristics of drug effects and economical situation, as well as conduct pharmaceutical monitoring actively so as to guarantee the safety and effectiveness of chemotherapy.

关 键 词：扁桃体癌 化疗方案 制订 药学监护 

分 类 号：R969.3[医药卫生—药理学]