免疫球蛋白E在Kimura病诊疗评估中的意义  

Significance of immunoglobulin E in evaluation of diagnosis and treatment of Kimura disease

作　　者：黄南[1] 程熠[2] 王迪[3] 祁姗姗[4] 

机构地区：[1]华中科技大学同济医学院附属同济医院过敏反应科,武汉430030 [2]华中科技大学同济医学院附属同济医院肿瘤科,武汉430030 [3]华中科技大学同济医学院附属同济医院血液内科,武汉430030 [4]湖北省武汉市中西医结合医院呼吸内科,430030

出　　处：《检验医学与临床》2017年第17期2526-2527,2530,共3页Laboratory Medicine and Clinic

摘　　要：目的评估免疫球蛋白E在Kimura病的早期诊断与治疗评估中的意义。方法回顾性分析2005-2013年确诊为Kimura病的27例患者的一般资料、临床表现、影像学检查、病理学检查及预后,并分析免疫球蛋白E检测的特点和意义。结果 27例患者总免疫球蛋白E水平均显著升高,但特异性免疫球蛋白E水平并无明显升高。经治疗好转后,患者总免疫球蛋白E水平较治疗前明显下降。结论对于慢性软组织肿胀患者进行免疫球蛋白E的总体计数及特异性免疫球蛋白E筛查可能有利于Kimura病的早期诊断和临床疗效判定。Objective To assess the significance of immunoglobulin E in early diagnosis and management evaluation of Kimura disease.Methods The general data,clinical manifestations,imaging examination,pathological examination and prognosis in 27 patients with Kimura disease during 2005-2013 were retrospectively analyzed.And the features and significance of immunoglobulin E detection were analyzed.Results The total immunoglobulin level was significantly increased in all 27 cases,but the specific immunoglobulin E level had no obvious increase.The total immunoglobulin E level after treatment was decreased compared with before treatment.Conclusion In the patients with chronic soft tissue swelling,the total immunoglobulin E counting and specific immunoglobulin E screening can be conducive to the early diagnosis and curative effect evaluation of Kimura disease.

关 键 词：KIMURA病 总免疫球蛋白E 特异性免疫球蛋白E 

分 类 号：R725.622.5[医药卫生—儿科]