介入治疗后辛伐他汀对急性心肌梗死早期左心室重构治疗效果  

The Effect of Simvastatin on Left Ventricular Remodeling in Early Stage of Acute Myocardial Infarction After Interventional Therapy

作　　者：高超[1] 

机构地区：[1]山东省聊城市高唐县人民医院急诊科,山东聊城252800

出　　处：《中国继续医学教育》2017年第19期147-148,共2页China Continuing Medical Education

摘　　要：目的介入治疗后辛伐他汀对急性心肌梗死早期左心室重构治疗效果。方法选取我院2016年1月—2017年1月共收治急性心肌梗死早期左心室重构患者78例作为研究对象。采用数字表法进行分组,对照组(n=39)采用常规治疗,观察组(n=39)在常规治疗的基础上,采用辛伐他汀治疗,对比分析两组患者左心室形态、构型等指标。结果观察组患者的C反应蛋白(hs-CRP)、左室射血分数(LVEF)、左室舒张末期容积(LVEDV)和左室收缩末期容积(LVESV)等指标均优于对照组,差异均具有统计学意义(P<0.05)。结论通过临床比较,急性心肌梗死患者介入治疗后,运用辛伐他汀进行治疗可抑制心室重构,对控制病情具有积极意义。Objective To investigate the effect of simvastatin on left ventricular remodeling in early stage of acute myocardial infarction after interventional therapy. Methods A total of 78 patients with left ventricular remodeling in acute myocardial infarction were selected from January 2016 to January 2017 in our hospital.The patients were divided into two groups by digital table, and the control group （n=39） received routine treatment, the observation group （n=39） was treated with simvastatin on the basis of conventional treatment, the left ventricular shape and configuration of the two groups were compared and analyzed. Results The indexes of protein （hs-CRP）, left ventricular ejection fraction （LVEF）, left vcntricular end diastolic volume （LVEDV） and left ventricular end systolic volume （LVESV） in the observation group were better than those in the control group, the differences were statistically significant （P〈0.05）. Conclusion The clinical treatment of patients with acute myocardial infarction after treatment, the use of simvastatin treatment can inhibit ventricular remodeling, the control of the disease has a positive significance.

关 键 词：急性心肌梗死 左心室重构 辛伐他汀 介入效果 

分 类 号：R54[医药卫生—心血管疾病]